diff --git a/src/posix/platform/hdlc_interface.cpp b/src/posix/platform/hdlc_interface.cpp
index d531d965b..f26ab644a 100644
--- a/src/posix/platform/hdlc_interface.cpp
+++ b/src/posix/platform/hdlc_interface.cpp
@@ -499,6 +499,7 @@ void HdlcInterface::HandleHdlcFrame(otError aError)
     }
     else
     {
+        mRxFrameBuffer.DiscardFrame();
         otLogWarnPlat("Error decoding hdlc frame: %s", otThreadErrorToString(aError));
     }
 }