diff --git a/configure.ac b/configure.ac
index d9e573f6c..1d645b71d 100644
--- a/configure.ac
+++ b/configure.ac
@@ -796,64 +796,6 @@ AC_SUBST(OPENTHREAD_ENABLE_MTD_NETWORK_DIAGNOSTIC)
 AM_CONDITIONAL([OPENTHREAD_ENABLE_MTD_NETWORK_DIAGNOSTIC], [test "${enable_mtd_network_diagnostic}" = "yes"])
 AC_DEFINE_UNQUOTED([OPENTHREAD_ENABLE_MTD_NETWORK_DIAGNOSTIC],[${OPENTHREAD_ENABLE_MTD_NETWORK_DIAGNOSTIC}],[Define to 1 to enable network diagnostic for MTD.])
 
-#
-# Platform UDP
-#
-
-AC_ARG_ENABLE(platform_udp,
-    [AS_HELP_STRING([--enable-platform-udp],[Enable platform UDP support @<:@default=no@:>@.])],
-    [
-        case "${enableval}" in
-        no|yes)
-            enable_platform_udp=${enableval}
-            ;;
-        *)
-            AC_MSG_ERROR([Invalid value ${enable_platform_udp} for --enable-platform-udp])
-            ;;
-        esac
-    ],
-    [enable_platform_udp=no])
-
-if test "$enable_platform_udp" = "yes"; then
-    OPENTHREAD_ENABLE_PLATFORM_UDP=1
-else
-    OPENTHREAD_ENABLE_PLATFORM_UDP=0
-fi
-
-AC_MSG_RESULT(${enable_platform_udp})
-AC_SUBST(OPENTHREAD_ENABLE_PLATFORM_UDP)
-AM_CONDITIONAL([OPENTHREAD_ENABLE_PLATFORM_UDP], [test "${enable_platform_udp}" = "yes"])
-AC_DEFINE_UNQUOTED([OPENTHREAD_ENABLE_PLATFORM_UDP], [${OPENTHREAD_ENABLE_PLATFORM_UDP}], [Define to 1 to enable platform UDP.])
-
-#
-# Platform Netif
-#
-
-AC_ARG_ENABLE(platform_netif,
-    [AS_HELP_STRING([--enable-platform-netif],[Enable platform Netif support @<:@default=no@:>@.])],
-    [
-        case "${enableval}" in
-        no|yes)
-            enable_platform_netif=${enableval}
-            ;;
-        *)
-            AC_MSG_ERROR([Invalid value ${enable_platform_netif} for --enable-platform-netif])
-            ;;
-        esac
-    ],
-    [enable_platform_netif=no])
-
-if test "$enable_platform_netif" = "yes"; then
-    OPENTHREAD_ENABLE_PLATFORM_NETIF=1
-else
-    OPENTHREAD_ENABLE_PLATFORM_NETIF=0
-fi
-
-AC_MSG_RESULT(${enable_platform_netif})
-AC_SUBST(OPENTHREAD_ENABLE_PLATFORM_NETIF)
-AM_CONDITIONAL([OPENTHREAD_ENABLE_PLATFORM_NETIF], [test "${enable_platform_netif}" = 'yes'])
-AC_DEFINE_UNQUOTED([OPENTHREAD_ENABLE_PLATFORM_NETIF], [${OPENTHREAD_ENABLE_PLATFORM_NETIF}], [Define to 1 to enable platform Netif.])
-
 #
 # Jam Detection
 #
diff --git a/examples/common-switches.mk b/examples/common-switches.mk
index a91513565..f556f3cb2 100644
--- a/examples/common-switches.mk
+++ b/examples/common-switches.mk
@@ -155,7 +155,7 @@ configure_OPTIONS              += --enable-mtd-network-diagnostic
 endif
 
 ifeq ($(PLATFORM_UDP),1)
-configure_OPTIONS              += --enable-platform-udp
+COMMONCFLAGS                   += -DOPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE=1
 endif
 
 # Enable features only required for reference device during certification.
diff --git a/examples/platforms/nrf52811/openthread-core-nrf52811-config.h b/examples/platforms/nrf52811/openthread-core-nrf52811-config.h
index cbcd5a6a0..bc473d2b8 100644
--- a/examples/platforms/nrf52811/openthread-core-nrf52811-config.h
+++ b/examples/platforms/nrf52811/openthread-core-nrf52811-config.h
@@ -141,13 +141,13 @@
 #endif
 
 /**
- * @def OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+ * @def OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
  *
  * Define to 1 if you want to support microsecond timer in platform.
  *
  */
-#ifndef OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
-#define OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER 1
+#ifndef OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
+#define OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE 1
 #endif
 
 /**
diff --git a/examples/platforms/nrf52840/openthread-core-nrf52840-config.h b/examples/platforms/nrf52840/openthread-core-nrf52840-config.h
index f824834fe..ec6efcc7f 100644
--- a/examples/platforms/nrf52840/openthread-core-nrf52840-config.h
+++ b/examples/platforms/nrf52840/openthread-core-nrf52840-config.h
@@ -163,13 +163,13 @@
 #endif
 
 /**
- * @def OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+ * @def OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
  *
  * Define to 1 if you want to support microsecond timer in platform.
  *
  */
-#ifndef OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
-#define OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER 1
+#ifndef OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
+#define OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE 1
 #endif
 
 /**
diff --git a/examples/platforms/posix/alarm.c b/examples/platforms/posix/alarm.c
index db613238e..208e0209c 100644
--- a/examples/platforms/posix/alarm.c
+++ b/examples/platforms/posix/alarm.c
@@ -283,7 +283,7 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
     if (sIsUsRunning)
     {
@@ -297,7 +297,7 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 }
 
 uint64_t otPlatTimeGet(void)
diff --git a/examples/platforms/posix/openthread-core-posix-config.h b/examples/platforms/posix/openthread-core-posix-config.h
index 5c641c50f..4273d4e98 100644
--- a/examples/platforms/posix/openthread-core-posix-config.h
+++ b/examples/platforms/posix/openthread-core-posix-config.h
@@ -112,12 +112,12 @@
 #endif // OPENTHREAD_RADIO
 
 /**
- * @def OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+ * @def OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
  *
  * Define to 1 if you want to support microsecond timer in platform.
  *
  */
-#define OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER 1
+#define OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE 1
 
 /**
  * @def CLI_COAP_SECURE_USE_COAP_DEFAULT_HANDLER
diff --git a/examples/platforms/posix/sim/alarm-sim.c b/examples/platforms/posix/sim/alarm-sim.c
index dc4780dc9..75fc72be7 100644
--- a/examples/platforms/posix/sim/alarm-sim.c
+++ b/examples/platforms/posix/sim/alarm-sim.c
@@ -121,7 +121,7 @@ int32_t platformAlarmGetNext(void)
         }
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
     if (sIsUsRunning)
     {
@@ -133,7 +133,7 @@ int32_t platformAlarmGetNext(void)
         }
     }
 
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
     return remaining;
 }
@@ -164,7 +164,7 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
     if (sIsUsRunning)
     {
@@ -178,7 +178,7 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 }
 
 uint64_t otPlatTimeGet(void)
diff --git a/src/core/Makefile.am b/src/core/Makefile.am
index f77221539..b4490d5c7 100644
--- a/src/core/Makefile.am
+++ b/src/core/Makefile.am
@@ -339,6 +339,7 @@ HEADERS_COMMON                             = \
     config/openthread-core-config-check.h    \
     config/openthread-core-default-config.h  \
     config/parent_search.h                   \
+    config/platform.h                        \
     crypto/aes_ccm.hpp                       \
     crypto/aes_ecb.hpp                       \
     crypto/ecdsa.hpp                         \
diff --git a/src/core/api/udp_api.cpp b/src/core/api/udp_api.cpp
index a51358cdb..30d08156f 100644
--- a/src/core/api/udp_api.cpp
+++ b/src/core/api/udp_api.cpp
@@ -128,7 +128,7 @@ void otUdpForwardReceive(otInstance *        aInstance,
 }
 #endif // OPENTHREAD_ENABLE_UDP_FORWARD
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
 otUdpSocket *otUdpGetSockets(otInstance *aInstance)
 {
     Instance &instance = *static_cast<Instance *>(aInstance);
diff --git a/src/core/common/instance.cpp b/src/core/common/instance.cpp
index f530a8f13..2c2745efd 100644
--- a/src/core/common/instance.cpp
+++ b/src/core/common/instance.cpp
@@ -51,7 +51,7 @@ otDEFINE_ALIGNED_VAR(gInstanceRaw, sizeof(Instance), uint64_t);
 Instance::Instance(void)
     : mTaskletScheduler()
     , mTimerMilliScheduler(*this)
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
     , mTimerMicroScheduler(*this)
 #endif
 #if OPENTHREAD_MTD || OPENTHREAD_FTD
diff --git a/src/core/common/instance.hpp b/src/core/common/instance.hpp
index 7146a63fa..703b37b6f 100644
--- a/src/core/common/instance.hpp
+++ b/src/core/common/instance.hpp
@@ -308,7 +308,7 @@ private:
 
     TaskletScheduler    mTaskletScheduler;
     TimerMilliScheduler mTimerMilliScheduler;
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
     TimerMicroScheduler mTimerMicroScheduler;
 #endif
 
@@ -703,7 +703,7 @@ template <> inline TimerMilliScheduler &Instance::Get(void)
     return mTimerMilliScheduler;
 }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 template <> inline TimerMicroScheduler &Instance::Get(void)
 {
     return mTimerMicroScheduler;
diff --git a/src/core/common/timer.cpp b/src/core/common/timer.cpp
index 38079df4e..4e50be166 100644
--- a/src/core/common/timer.cpp
+++ b/src/core/common/timer.cpp
@@ -212,7 +212,7 @@ exit:
     return;
 }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 const TimerScheduler::AlarmApi TimerMicroScheduler::sAlarmMicroApi = {&otPlatAlarmMicroStartAt, &otPlatAlarmMicroStop,
                                                                       &otPlatAlarmMicroGetNow};
 
@@ -238,6 +238,6 @@ extern "C" void otPlatAlarmMicroFired(otInstance *aInstance)
 exit:
     return;
 }
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
 } // namespace ot
diff --git a/src/core/common/timer.hpp b/src/core/common/timer.hpp
index 1032b548c..3e000a388 100644
--- a/src/core/common/timer.hpp
+++ b/src/core/common/timer.hpp
@@ -412,7 +412,7 @@ private:
     static const AlarmApi sAlarmMilliApi;
 };
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 class TimerMicroScheduler;
 
 /**
@@ -512,7 +512,7 @@ public:
 private:
     static const AlarmApi sAlarmMicroApi;
 };
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
 /**
  * @}
diff --git a/src/core/config/openthread-core-config-check.h b/src/core/config/openthread-core-config-check.h
index 0f06bd8b7..a5103631d 100644
--- a/src/core/config/openthread-core-config-check.h
+++ b/src/core/config/openthread-core-config-check.h
@@ -34,8 +34,8 @@
 #ifndef OPENTHREAD_CORE_CONFIG_CHECK_H_
 #define OPENTHREAD_CORE_CONFIG_CHECK_H_
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP && OPENTHREAD_ENABLE_UDP_FORWARD
-#error "OPENTHREAD_ENABLE_PLATFORM_UDP and OPENTHREAD_ENABLE_UDP_FORWARD must not both be set."
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE && OPENTHREAD_ENABLE_UDP_FORWARD
+#error "OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE and OPENTHREAD_ENABLE_UDP_FORWARD must not both be set."
 #endif
 
 /*
diff --git a/src/core/config/openthread-core-default-config.h b/src/core/config/openthread-core-default-config.h
index 15c273555..f6dae7570 100644
--- a/src/core/config/openthread-core-default-config.h
+++ b/src/core/config/openthread-core-default-config.h
@@ -75,16 +75,6 @@
 #define OPENTHREAD_CONFIG_STACK_VERSION_MINOR 1
 #endif
 
-/**
- * @def OPENTHREAD_CONFIG_PLATFORM_INFO
- *
- * The platform-specific string to insert into the OpenThread version string.
- *
- */
-#ifndef OPENTHREAD_CONFIG_PLATFORM_INFO
-#define OPENTHREAD_CONFIG_PLATFORM_INFO "NONE"
-#endif
-
 /**
  * @def OPENTHREAD_CONFIG_NUM_MESSAGE_BUFFERS
  *
@@ -247,18 +237,6 @@
 #define OPENTHREAD_CONFIG_SNTP_MAX_RETRANSMIT 2
 #endif
 
-/**
- * @def OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT
- *
- * The message pool is managed by platform defined logic when this flag is set.
- * This feature would typically be used when operating in a multi-threaded system
- * and multiple threads need to access the message pool.
- *
- */
-#ifndef OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT
-#define OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT 0
-#endif
-
 /**
  * @def OPENTHREAD_CONFIG_STORE_FRAME_COUNTER_AHEAD
  *
@@ -308,36 +286,6 @@
 #define OPENTHREAD_CONFIG_ENABLE_BUILTIN_MBEDTLS 1
 #endif
 
-/**
- * @def OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT
- *
- * The assert is managed by platform defined logic when this flag is set.
- *
- */
-#ifndef OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT
-#define OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT 0
-#endif
-
-/**
- * @def OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
- *
- * Define to 1 if you want to enable microsecond backoff timer implemented in platform.
- *
- */
-#ifndef OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
-#define OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER 0
-#endif
-
-/**
- * @def OPENTHREAD_CONFIG_ENABLE_PLATFORM_EUI64_CUSTOM_SOURCE
- *
- * Allows to define custom otPlatRadioGetIeeeEui64 function to retrieve EUI-64.
- *
- */
-#ifndef OPENTHREAD_CONFIG_ENABLE_PLATFORM_EUI64_CUSTOM_SOURCE
-#define OPENTHREAD_CONFIG_ENABLE_PLATFORM_EUI64_CUSTOM_SOURCE 0
-#endif
-
 /**
  * @def OPENTHREAD_CONFIG_HEAP_SIZE
  *
diff --git a/src/core/config/platform.h b/src/core/config/platform.h
new file mode 100644
index 000000000..7507ac082
--- /dev/null
+++ b/src/core/config/platform.h
@@ -0,0 +1,100 @@
+/*
+ *  Copyright (c) 2019, The OpenThread Authors.
+ *  All rights reserved.
+ *
+ *  Redistribution and use in source and binary forms, with or without
+ *  modification, are permitted provided that the following conditions are met:
+ *  1. Redistributions of source code must retain the above copyright
+ *     notice, this list of conditions and the following disclaimer.
+ *  2. Redistributions in binary form must reproduce the above copyright
+ *     notice, this list of conditions and the following disclaimer in the
+ *     documentation and/or other materials provided with the distribution.
+ *  3. Neither the name of the copyright holder nor the
+ *     names of its contributors may be used to endorse or promote products
+ *     derived from this software without specific prior written permission.
+ *
+ *  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+ *  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+ *  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+ *  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+ *  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+ *  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+ *  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+ *  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+ *  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+ *  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+ *  POSSIBILITY OF SUCH DAMAGE.
+ */
+
+/**
+ * @file
+ *   This file includes compile-time configurations for platform-specific services.
+ *
+ */
+
+#ifndef CONFIG_PLATFORM_H_
+#define CONFIG_PLATFORM_H_
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_INFO
+ *
+ * The platform-specific string to insert into the OpenThread version string.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_INFO
+#define OPENTHREAD_CONFIG_PLATFORM_INFO "NONE"
+#endif
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT
+ *
+ * The message pool is managed by platform defined logic when this flag is set.
+ * This feature would typically be used when operating in a multi-threaded system
+ * and multiple threads need to access the message pool.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT
+#define OPENTHREAD_CONFIG_PLATFORM_MESSAGE_MANAGEMENT 0
+#endif
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT
+ *
+ * The assert is managed by platform defined logic when this flag is set.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT
+#define OPENTHREAD_CONFIG_PLATFORM_ASSERT_MANAGEMENT 0
+#endif
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
+ *
+ * Define to 1 to enable platform NETIF support.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
+#define OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE 0
+#endif
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
+ *
+ * Define to 1 to enable platform UDP support.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
+#define OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE 0
+#endif
+
+/**
+ * @def OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
+ *
+ * Define to 1 if you want to enable microsecond backoff timer implemented in platform.
+ *
+ */
+#ifndef OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
+#define OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE 0
+#endif
+
+#endif // CONFIG_PLATFORM_H_
diff --git a/src/core/mac/sub_mac.cpp b/src/core/mac/sub_mac.cpp
index 3049826a9..05352a474 100644
--- a/src/core/mac/sub_mac.cpp
+++ b/src/core/mac/sub_mac.cpp
@@ -256,7 +256,7 @@ void SubMac::StartCsmaBackoff(void)
         otPlatRadioSleep(&GetInstance());
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
     mTimer.Start(backoff);
 #else
     mTimer.Start(backoff / 1000UL);
@@ -304,7 +304,7 @@ void SubMac::HandleTransmitStarted(Frame &aFrame)
 {
     if (ShouldHandleAckTimeout() && aFrame.GetAckRequest())
     {
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
         mTimer.Start(kAckTimeout * 1000UL);
 #else
         mTimer.Start(kAckTimeout);
diff --git a/src/core/mac/sub_mac.hpp b/src/core/mac/sub_mac.hpp
index 6c86321da..f30d2d022 100644
--- a/src/core/mac/sub_mac.hpp
+++ b/src/core/mac/sub_mac.hpp
@@ -413,7 +413,7 @@ private:
         kMinBackoff        = 1,  ///< Minimum backoff (milliseconds).
         kAckTimeout        = 16, ///< Timeout for waiting on an ACK (milliseconds).
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
         kEnergyScanRssiSampleInterval = 128, ///< RSSI sample interval during energy scan, 128 usec
 #else
         kEnergyScanRssiSampleInterval = 1, ///< RSSI sample interval during energy scan, 1 ms
@@ -467,7 +467,7 @@ private:
     Callbacks          mCallbacks;
     otLinkPcapCallback mPcapCallback;
     void *             mPcapCallbackContext;
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
     TimerMicro mTimer;
 #else
     TimerMilli mTimer;
diff --git a/src/core/net/ip6.cpp b/src/core/net/ip6.cpp
index 374fd7bc8..5cf051a32 100644
--- a/src/core/net/ip6.cpp
+++ b/src/core/net/ip6.cpp
@@ -732,7 +732,7 @@ otError Ip6::ProcessReceiveCallback(const Message &    aMessage,
 
                 break;
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP == 0
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE == 0
             case kCoapUdpPort:
 
                 // do not pass TMF messages
@@ -742,7 +742,7 @@ otError Ip6::ProcessReceiveCallback(const Message &    aMessage,
                 }
 
                 break;
-#endif // OPENTHREAD_ENABLE_PLATFORM_UDP
+#endif // OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
 
             default:
 #if OPENTHREAD_FTD
diff --git a/src/core/net/udp6.cpp b/src/core/net/udp6.cpp
index 126ea10a2..13f0c2fcf 100644
--- a/src/core/net/udp6.cpp
+++ b/src/core/net/udp6.cpp
@@ -48,7 +48,7 @@ using ot::Encoding::BigEndian::HostSwap16;
 namespace ot {
 namespace Ip6 {
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
 static bool IsMle(Instance &aInstance, uint16_t aPort)
 {
 #if OPENTHREAD_FTD
@@ -79,13 +79,13 @@ otError UdpSocket::Open(otUdpReceive aHandler, void *aContext)
     mHandler = aHandler;
     mContext = aContext;
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     SuccessOrExit(error = otPlatUdpSocket(this));
 #endif
 
     Get<Udp>().AddSocket(*this);
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
 exit:
 #endif
     return error;
@@ -102,12 +102,12 @@ otError UdpSocket::Bind(const SockAddr &aSockAddr)
         do
         {
             mSockName.mPort = Get<Udp>().GetEphemeralPort();
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
             error = otPlatUdpBind(this);
 #endif
         } while (error != OT_ERROR_NONE);
     }
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     else if (!IsMle(GetInstance(), mSockName.mPort))
     {
         error = otPlatUdpBind(this);
@@ -123,7 +123,7 @@ otError UdpSocket::Connect(const SockAddr &aSockAddr)
 
     mPeerName = aSockAddr;
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     if (!IsMle(GetInstance(), mSockName.mPort))
     {
         error = otPlatUdpConnect(this);
@@ -136,7 +136,7 @@ otError UdpSocket::Close(void)
 {
     otError error = OT_ERROR_NONE;
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     SuccessOrExit(error = otPlatUdpClose(this));
 #endif
 
@@ -144,7 +144,7 @@ otError UdpSocket::Close(void)
     memset(&mSockName, 0, sizeof(mSockName));
     memset(&mPeerName, 0, sizeof(mPeerName));
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
 exit:
 #endif
     return error;
@@ -185,7 +185,7 @@ otError UdpSocket::SendTo(Message &aMessage, const MessageInfo &aMessageInfo)
 
     messageInfoLocal.SetSockPort(GetSockName().mPort);
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     if (!IsMle(GetInstance(), mSockName.mPort) &&
         !(mSockName.mPort == ot::kCoapUdpPort && aMessage.GetSubType() == Message::kSubTypeJoinerEntrust))
     {
@@ -377,7 +377,7 @@ otError Udp::HandleMessage(Message &aMessage, MessageInfo &aMessageInfo)
     aMessageInfo.mPeerPort = udpHeader.GetSourcePort();
     aMessageInfo.mSockPort = udpHeader.GetDestinationPort();
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     VerifyOrExit(IsMle(GetInstance(), aMessageInfo.mSockPort));
 #endif
 
diff --git a/src/core/net/udp6.hpp b/src/core/net/udp6.hpp
index ff6f340a0..4512624e0 100644
--- a/src/core/net/udp6.hpp
+++ b/src/core/net/udp6.hpp
@@ -328,7 +328,7 @@ public:
      */
     void UpdateChecksum(Message &aMessage, uint16_t aChecksum);
 
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     otUdpSocket *GetUdpSockets(void) { return mSockets; }
 #endif
 
diff --git a/src/core/openthread-core-config.h b/src/core/openthread-core-config.h
index 3651a63b2..2a56396b3 100644
--- a/src/core/openthread-core-config.h
+++ b/src/core/openthread-core-config.h
@@ -63,6 +63,7 @@
 #include "config/mac.h"
 #include "config/mle.h"
 #include "config/parent_search.h"
+#include "config/platform.h"
 
 #if OPENTHREAD_CONFIG_COAP_SECURE_API_ENABLE || OPENTHREAD_CONFIG_BORDER_AGENT_ENABLE || \
     OPENTHREAD_CONFIG_COMMISSIONER_ENABLE || OPENTHREAD_CONFIG_JOINER_ENABLE
diff --git a/src/posix/Makefile-posix b/src/posix/Makefile-posix
index 34ee98d75..73c86cc64 100644
--- a/src/posix/Makefile-posix
+++ b/src/posix/Makefile-posix
@@ -92,7 +92,7 @@ configure_OPTIONS              += --host=$(HOST)
 endif
 
 ifeq ($(PLATFORM_NETIF),1)
-configure_OPTIONS              += --enable-platform-netif
+COMMONCFLAGS                   += -DOPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE=1
 endif
 
 ifneq ($(READLINE),)
diff --git a/src/posix/main.c b/src/posix/main.c
index 00da24ae4..5643200af 100644
--- a/src/posix/main.c
+++ b/src/posix/main.c
@@ -93,7 +93,7 @@ int main(int argc, char *argv[])
 #if OPENTHREAD_POSIX_APP_TYPE == OPENTHREAD_POSIX_APP_TYPE_NCP
     otNcpInit(instance);
 #elif OPENTHREAD_POSIX_APP_TYPE == OPENTHREAD_POSIX_APP_TYPE_CLI
-#if OPENTHREAD_ENABLE_PLATFORM_NETIF
+#if OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
     otSysInitNetif(instance);
 #endif
 #if OPENTHREAD_USE_CONSOLE
diff --git a/src/posix/platform/Makefile.am b/src/posix/platform/Makefile.am
index b0aa68e70..cbc4e260a 100644
--- a/src/posix/platform/Makefile.am
+++ b/src/posix/platform/Makefile.am
@@ -51,13 +51,8 @@ libopenthread_posix_a_SOURCES             = \
     sim.c                                   \
     system.c                                \
     uart.c                                  \
-    $(NULL)
-
-if OPENTHREAD_ENABLE_PLATFORM_UDP
-libopenthread_posix_a_SOURCES            += \
     udp.cpp                                 \
     $(NULL)
-endif
 
 noinst_HEADERS                            = \
     openthread-system.h                     \
diff --git a/src/posix/platform/alarm.c b/src/posix/platform/alarm.c
index 22a400ddb..bb659af63 100644
--- a/src/posix/platform/alarm.c
+++ b/src/posix/platform/alarm.c
@@ -44,7 +44,7 @@
 static bool     sIsMsRunning = false;
 static uint32_t sMsAlarm     = 0;
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 static bool     sIsUsRunning = false;
 static uint32_t sUsAlarm     = 0;
 #endif
@@ -96,7 +96,7 @@ void otPlatAlarmMilliStop(otInstance *aInstance)
     sIsMsRunning = false;
 }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 uint32_t otPlatAlarmMicroGetNow(void)
 {
     return (uint32_t)(otSysGetTime());
@@ -116,7 +116,7 @@ void otPlatAlarmMicroStop(otInstance *aInstance)
 
     sIsUsRunning = false;
 }
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
 void platformAlarmUpdateTimeout(struct timeval *aTimeout)
 {
@@ -133,7 +133,7 @@ void platformAlarmUpdateTimeout(struct timeval *aTimeout)
         remaining -= (now % US_PER_MS);
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
     if (sIsUsRunning)
     {
         int32_t usRemaining = (int32_t)(sUsAlarm - (uint32_t)now);
@@ -143,7 +143,7 @@ void platformAlarmUpdateTimeout(struct timeval *aTimeout)
             remaining = usRemaining;
         }
     }
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
 exit:
     if (remaining <= 0)
@@ -191,7 +191,7 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 
     if (sIsUsRunning)
     {
@@ -205,5 +205,5 @@ void platformAlarmProcess(otInstance *aInstance)
         }
     }
 
-#endif // OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#endif // OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
 }
diff --git a/src/posix/platform/netif.cpp b/src/posix/platform/netif.cpp
index 280a182ef..a634d8c89 100644
--- a/src/posix/platform/netif.cpp
+++ b/src/posix/platform/netif.cpp
@@ -61,7 +61,7 @@
 #include "common/logging.hpp"
 #include "net/ip6_address.hpp"
 
-#if OPENTHREAD_ENABLE_PLATFORM_NETIF
+#if OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
 
 #ifndef OPENTHREAD_POSIX_TUN_DEVICE
 #define OPENTHREAD_POSIX_TUN_DEVICE "/dev/net/tun"
@@ -410,7 +410,7 @@ void platformNetifInit(otInstance *aInstance)
     VerifyOrExit(sTunIndex > 0);
 
     strncpy(sTunName, ifr.ifr_name, sizeof(sTunName));
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     platformUdpInit(sTunName);
 #endif
 
@@ -504,4 +504,4 @@ exit:
     return;
 }
 
-#endif // OPENTHREAD_ENABLE_PLATFORM_NETIF
+#endif // OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
diff --git a/src/posix/platform/system.c b/src/posix/platform/system.c
index 7ca077881..4b6f43d17 100644
--- a/src/posix/platform/system.c
+++ b/src/posix/platform/system.c
@@ -153,7 +153,7 @@ otInstance *otSysInit(int aArgCount, char *aArgVector[])
     platformAlarmInit(speedUpFactor);
     platformRadioInit(radioFile, radioConfig, reset);
     platformRandomInit();
-#if OPENTHREAD_ENABLE_PLATFORM_UDP && OPENTHREAD_ENABLE_PLATFORM_NETIF == 0
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE && OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE == 0
     platformUdpInit(getenv("PLATFORM_NETIF"));
 #endif
 
@@ -173,7 +173,7 @@ otInstance *otSysInit(int aArgCount, char *aArgVector[])
     return instance;
 }
 
-#if OPENTHREAD_ENABLE_PLATFORM_NETIF
+#if OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
 void otSysInitNetif(otInstance *aInstance)
 {
     platformNetifInit(aInstance);
@@ -226,10 +226,10 @@ void otSysMainloopUpdate(otInstance *aInstance, otSysMainloopContext *aMainloop)
     platformAlarmUpdateTimeout(&aMainloop->mTimeout);
     platformUartUpdateFdSet(&aMainloop->mReadFdSet, &aMainloop->mWriteFdSet, &aMainloop->mErrorFdSet,
                             &aMainloop->mMaxFd);
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     platformUdpUpdateFdSet(aInstance, &aMainloop->mReadFdSet, &aMainloop->mMaxFd);
 #endif
-#if OPENTHREAD_ENABLE_PLATFORM_NETIF
+#if OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
     platformNetifUpdateFdSet(&aMainloop->mReadFdSet, &aMainloop->mWriteFdSet, &aMainloop->mErrorFdSet,
                              &aMainloop->mMaxFd);
 #endif
@@ -299,10 +299,10 @@ void otSysMainloopProcess(otInstance *aInstance, const otSysMainloopContext *aMa
 #endif
     platformUartProcess(&aMainloop->mReadFdSet, &aMainloop->mWriteFdSet, &aMainloop->mErrorFdSet);
     platformAlarmProcess(aInstance);
-#if OPENTHREAD_ENABLE_PLATFORM_NETIF
+#if OPENTHREAD_CONFIG_PLATFORM_NETIF_ENABLE
     platformNetifProcess(&aMainloop->mReadFdSet, &aMainloop->mWriteFdSet, &aMainloop->mErrorFdSet);
 #endif
-#if OPENTHREAD_ENABLE_PLATFORM_UDP
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
     platformUdpProcess(aInstance, &aMainloop->mReadFdSet);
 #endif
 }
diff --git a/src/posix/platform/udp.cpp b/src/posix/platform/udp.cpp
index 935e43314..46616f8fc 100644
--- a/src/posix/platform/udp.cpp
+++ b/src/posix/platform/udp.cpp
@@ -53,6 +53,8 @@
 
 #include "common/code_utils.hpp"
 
+#if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
+
 static uint32_t sPlatNetifIndex = 0;
 
 static const size_t kMaxUdpSize = 1280;
@@ -447,3 +449,5 @@ void platformUdpProcess(otInstance *aInstance, const fd_set *aReadFdSet)
 exit:
     return;
 }
+
+#endif // #if OPENTHREAD_CONFIG_PLATFORM_UDP_ENABLE
diff --git a/tests/fuzz/fuzzer_platform.c b/tests/fuzz/fuzzer_platform.c
index 7357f40e3..e07f224fd 100644
--- a/tests/fuzz/fuzzer_platform.c
+++ b/tests/fuzz/fuzzer_platform.c
@@ -82,7 +82,7 @@ void FuzzerPlatformProcess(otInstance *aInstance)
             otPlatAlarmMilliFired(aInstance);
         }
 
-#if OPENTHREAD_CONFIG_ENABLE_PLATFORM_USEC_TIMER
+#if OPENTHREAD_CONFIG_PLATFORM_USEC_TIMER_ENABLE
         if (sAlarmMicro.isRunning && sAlarmNow >= sAlarmMicro.fire)
         {
             sAlarmMicro.isRunning = false;