diff --git a/src/lib/spinel/spinel_driver.cpp b/src/lib/spinel/spinel_driver.cpp
index b953d2969..d88d55df9 100644
--- a/src/lib/spinel/spinel_driver.cpp
+++ b/src/lib/spinel/spinel_driver.cpp
@@ -124,8 +124,10 @@ void SpinelDriver::ResetCoprocessor(bool aSoftwareReset)
     bool hardwareReset;
     bool resetDone = false;
 
+#if OPENTHREAD_CONFIG_MULTIPAN_RCP_ENABLE
     // Avoid resetting the device twice in a row in Multipan RCP architecture
     VerifyOrExit(!mIsCoprocessorReady, resetDone = true);
+#endif
 
     mWaitingKey = SPINEL_PROP_LAST_STATUS;