diff --git a/CMakeLists.txt b/CMakeLists.txt
index b13e96a49..9193771c9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -37,6 +37,7 @@ project(openthread VERSION ${OT_DEFAULT_VERSION})
 option(OT_BUILD_EXECUTABLES "Build executables" ON)
 option(OT_COVERAGE "enable coverage" OFF)
 set(OT_EXTERNAL_MBEDTLS "" CACHE STRING "Specify external mbedtls library")
+option(OT_MBEDTLS_THREADING "enable mbedtls threading" OFF)
 
 add_library(ot-config INTERFACE)
 
@@ -159,7 +160,10 @@ if(OT_PLATFORM STREQUAL "posix")
     add_subdirectory("${PROJECT_SOURCE_DIR}/src/posix/platform")
 elseif(OT_PLATFORM STREQUAL "external")
     # skip in this case
-elseif(OT_PLATFORM)
+elseif(OT_PLATFORM MATCHES "^nrf*")
+    target_include_directories(ot-config INTERFACE ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/${OT_PLATFORM})
+    add_subdirectory("${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx")
+else()
     target_include_directories(ot-config INTERFACE ${PROJECT_SOURCE_DIR}/examples/platforms/${OT_PLATFORM})
     add_subdirectory("${PROJECT_SOURCE_DIR}/examples/platforms/${OT_PLATFORM}")
 endif()
diff --git a/etc/cmake/functions.cmake b/etc/cmake/functions.cmake
index 4cb0bef8c..7c5e62a68 100755
--- a/etc/cmake/functions.cmake
+++ b/etc/cmake/functions.cmake
@@ -30,14 +30,16 @@
 function(ot_get_platforms arg_platforms)
     list(APPEND result "NO" "posix" "external")
     set(platforms_dir "${PROJECT_SOURCE_DIR}/examples/platforms")
-    file(GLOB platforms RELATIVE "${platforms_dir}" "${platforms_dir}/*")
+    file(GLOB platforms RELATIVE "${platforms_dir}" "${platforms_dir}/*"
+            RELATIVE "${platforms_dir}/nrf528xx" "${platforms_dir}/nrf528xx/nrf*")
     foreach(platform IN LISTS platforms)
-        if(IS_DIRECTORY "${platforms_dir}/${platform}")
+        if((IS_DIRECTORY "${platforms_dir}/${platform}") OR
+            (IS_DIRECTORY "${platforms_dir}/nrf528xx/${platform}"))
             list(APPEND result "${platform}")
         endif()
     endforeach()
 
-    list(REMOVE_ITEM result utils)
+    list(REMOVE_ITEM result utils nrf528xx)
     list(SORT result)
     set(${arg_platforms} "${result}" PARENT_SCOPE)
 endfunction()
diff --git a/examples/platforms/nrf528xx/CMakeLists.txt b/examples/platforms/nrf528xx/CMakeLists.txt
new file mode 100644
index 000000000..8b474e021
--- /dev/null
+++ b/examples/platforms/nrf528xx/CMakeLists.txt
@@ -0,0 +1,103 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+if(OT_NCP_SPI)
+    list(APPEND OT_PLATFORM_DEFINES "SPIS_AS_SERIAL_TRANSPORT=1")
+else()
+    option(OT_USB "enable nrf USB as serial transport support")
+    if(OT_USB)
+        list(APPEND OT_PLATFORM_DEFINES "USB_CDC_AS_SERIAL_TRANSPORT=1")
+    else()
+        list(APPEND OT_PLATFORM_DEFINES "UART_AS_SERIAL_TRANSPORT=1")
+    endif()
+endif()
+
+set(NRF_COMM_SOURCES
+    src/alarm.c
+    src/diag.c
+    src/entropy.c
+    src/fem.c
+    src/flash.c
+    src/logging.c
+    src/misc.c
+    src/radio.c
+    src/system.c
+    src/temp.c
+)
+
+set(NRF_TRANSPORT_SOURCES
+    src/transport/spi-slave.c
+    src/transport/transport.c
+    src/transport/uart.c
+    src/transport/usb-cdc-uart.c
+)
+
+set(NRF_SINGLEPHY_SOURCES
+    src/flash_nosd.c
+)
+
+set(NRF_SOFTDEVICE_SOURCES
+    src/flash_sd.c
+    src/softdevice.c
+)
+
+set(NRF_INCLUDES
+    ${CMAKE_CURRENT_SOURCE_DIR}/src
+    ${PROJECT_SOURCE_DIR}/examples/platforms
+    ${PROJECT_SOURCE_DIR}/src/core
+)
+
+if(OT_PLATFORM STREQUAL "nrf52811")
+    set(NRF_TRANSPORT_SOURCES
+        src/transport/spi-slave.c
+        src/transport/transport.c
+        src/transport/uart.c
+    )
+    set(NRF52811_3RD_LIBS
+        nordicsemi-nrf52811-radio-driver
+        nordicsemi-nrf52811-sdk
+        jlinkrtt
+    )
+    include(nrf52811/nrf52811.cmake)
+elseif(OT_PLATFORM STREQUAL "nrf52833")
+    set(NRF52833_3RD_LIBS
+        nordicsemi-nrf52833-radio-driver
+        nordicsemi-nrf52833-radio-driver-softdevice
+        nordicsemi-nrf52833-sdk
+        jlinkrtt
+    )
+    include(nrf52833/nrf52833.cmake)
+elseif(OT_PLATFORM STREQUAL "nrf52840")
+    set(NRF52840_3RD_LIBS
+        nordicsemi-nrf52840-radio-driver
+        nordicsemi-nrf52840-radio-driver-softdevice
+        nordicsemi-nrf52840-sdk
+        jlinkrtt
+    )
+    include(nrf52840/nrf52840.cmake)
+endif()
diff --git a/examples/platforms/nrf528xx/nrf52811/arm-none-eabi.cmake b/examples/platforms/nrf528xx/nrf52811/arm-none-eabi.cmake
new file mode 100644
index 000000000..a2e520ae7
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52811/arm-none-eabi.cmake
@@ -0,0 +1,56 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(CMAKE_SYSTEM_NAME              Generic)
+set(CMAKE_SYSTEM_PROCESSOR         ARM)
+
+set(CMAKE_C_COMPILER               arm-none-eabi-gcc)
+set(CMAKE_CXX_COMPILER             arm-none-eabi-g++)
+set(CMAKE_ASM_COMPILER             arm-none-eabi-as)
+set(CMAKE_RANLIB                   arm-none-eabi-ranlib)
+
+execute_process(COMMAND ${CMAKE_CXX_COMPILER} -dumpversion OUTPUT_VARIABLE COMPILER_VERSION OUTPUT_STRIP_TRAILING_WHITESPACE)
+
+set(COMMON_C_FLAGS                 "-mcpu=cortex-m4 -mfloat-abi=soft -mthumb -mabi=aapcs -fdata-sections -ffunction-sections")
+
+if(COMPILER_VERSION VERSION_GREATER_EQUAL 7)
+    set(COMMON_C_FLAGS             "${COMMON_C_FLAGS} -Wno-expansion-to-defined")
+endif()
+
+set(CMAKE_C_FLAGS_INIT             "${COMMON_C_FLAGS} -std=gnu99")
+set(CMAKE_CXX_FLAGS_INIT           "${COMMON_C_FLAGS} -fno-exceptions -fno-rtti")
+set(CMAKE_ASM_FLAGS_INIT           "${COMMON_C_FLAGS} -x assembler-with-cpp")
+set(CMAKE_EXE_LINKER_FLAGS_INIT    "${COMMON_C_FLAGS} -specs=nano.specs -specs=nosys.specs")
+
+set(CMAKE_C_FLAGS_DEBUG            "-Og -g")
+set(CMAKE_CXX_FLAGS_DEBUG          "-Og -g")
+set(CMAKE_ASM_FLAGS_DEBUG          "-g")
+
+set(CMAKE_C_FLAGS_RELEASE          "-Os")
+set(CMAKE_CXX_FLAGS_RELEASE        "-Os")
+set(CMAKE_ASM_FLAGS_RELEASE        "")
diff --git a/examples/platforms/nrf528xx/nrf52811/nrf52811.cmake b/examples/platforms/nrf528xx/nrf52811/nrf52811.cmake
new file mode 100644
index 000000000..ffe837e6b
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52811/nrf52811.cmake
@@ -0,0 +1,179 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(OT_PLATFORM_LIB "openthread-nrf52811" "openthread-nrf52811-transport" PARENT_SCOPE)
+
+if(NOT OT_CONFIG)
+    set(OT_CONFIG "${CMAKE_CURRENT_SOURCE_DIR}/nrf52811/openthread-core-nrf52811-config.h")
+    set(OT_CONFIG ${OT_CONFIG} PARENT_SCOPE)
+endif()
+
+set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52811/nrf52811.ld")
+
+set(COMM_FLAGS
+    -DDISABLE_CC310=1
+    -DCONFIG_GPIO_AS_PINRESET
+    -DNRF52811_XXAA
+    -DUSE_APP_CONFIG=1
+    -Wno-unused-parameter
+    -Wno-expansion-to-defined
+)
+
+list(APPEND OT_PLATFORM_DEFINES
+    "OPENTHREAD_CORE_CONFIG_PLATFORM_CHECK_FILE=\"openthread-core-nrf52811-config-check.h\""
+)
+
+list(APPEND OT_PUBLIC_INCLUDES
+    "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/mbedtls_plat_config"
+    "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/mdk"
+    "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/cmsis"
+)
+
+set(OT_PLATFORM_DEFINES ${OT_PLATFORM_DEFINES} PARENT_SCOPE)
+target_compile_definitions(ot-config INTERFACE
+    "MBEDTLS_USER_CONFIG_FILE=\"nrf52811-mbedtls-config.h\""
+)
+set(OT_PUBLIC_INCLUDES ${OT_PUBLIC_INCLUDES} PARENT_SCOPE)
+
+if(OT_CFLAGS MATCHES "-pedantic-errors")
+    string(REPLACE "-pedantic-errors" "" OT_CFLAGS "${OT_CFLAGS}")
+endif()
+
+list(APPEND OT_PLATFORM_DEFINES "OPENTHREAD_PROJECT_CORE_CONFIG_FILE=\"${OT_CONFIG}\"")
+
+add_library(openthread-nrf52811
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+add_library(openthread-nrf52811-transport
+    ${NRF_TRANSPORT_SOURCES}
+)
+
+add_library(openthread-nrf52811-sdk
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+set_target_properties(openthread-nrf52811 openthread-nrf52811-transport openthread-nrf52811-sdk
+    PROPERTIES
+        C_STANDARD 99
+        CXX_STANDARD 11
+)
+
+target_link_libraries(openthread-nrf52811
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52811_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52811-transport
+    PUBLIC
+        ${OT_MBEDTLS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        nordicsemi-nrf52811-sdk
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52811-sdk
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52811_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_compile_definitions(openthread-nrf52811
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52811-transport
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52811-sdk
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_options(openthread-nrf52811
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DRAAL_SINGLE_PHY=1
+)
+
+target_compile_options(openthread-nrf52811-transport
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+)
+
+target_compile_options(openthread-nrf52811-sdk
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DRAAL_SINGLE_PHY=1
+)
+
+target_include_directories(openthread-nrf52811
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52811
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52811-transport
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52811
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52811-sdk
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52811
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
diff --git a/examples/platforms/nrf528xx/nrf52833/arm-none-eabi.cmake b/examples/platforms/nrf528xx/nrf52833/arm-none-eabi.cmake
new file mode 100644
index 000000000..3147abe0c
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52833/arm-none-eabi.cmake
@@ -0,0 +1,56 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(CMAKE_SYSTEM_NAME              Generic)
+set(CMAKE_SYSTEM_PROCESSOR         ARM)
+
+set(CMAKE_C_COMPILER               arm-none-eabi-gcc)
+set(CMAKE_CXX_COMPILER             arm-none-eabi-g++)
+set(CMAKE_ASM_COMPILER             arm-none-eabi-as)
+set(CMAKE_RANLIB                   arm-none-eabi-ranlib)
+
+execute_process(COMMAND ${CMAKE_CXX_COMPILER} -dumpversion OUTPUT_VARIABLE COMPILER_VERSION OUTPUT_STRIP_TRAILING_WHITESPACE)
+
+set(COMMON_C_FLAGS                 "-mcpu=cortex-m4 -mfloat-abi=hard -mfpu=fpv4-sp-d16 -mthumb -mabi=aapcs -fdata-sections -ffunction-sections")
+
+if(COMPILER_VERSION VERSION_GREATER_EQUAL 7)
+    set(COMMON_C_FLAGS             "${COMMON_C_FLAGS} -Wno-expansion-to-defined")
+endif()
+
+set(CMAKE_C_FLAGS_INIT             "${COMMON_C_FLAGS} -std=gnu99")
+set(CMAKE_CXX_FLAGS_INIT           "${COMMON_C_FLAGS} -fno-exceptions -fno-rtti")
+set(CMAKE_ASM_FLAGS_INIT           "${COMMON_C_FLAGS} -x assembler-with-cpp")
+set(CMAKE_EXE_LINKER_FLAGS_INIT    "${COMMON_C_FLAGS} -specs=nano.specs -specs=nosys.specs")
+
+set(CMAKE_C_FLAGS_DEBUG            "-Og -g")
+set(CMAKE_CXX_FLAGS_DEBUG          "-Og -g")
+set(CMAKE_ASM_FLAGS_DEBUG          "-g")
+
+set(CMAKE_C_FLAGS_RELEASE          "-Os")
+set(CMAKE_CXX_FLAGS_RELEASE        "-Os")
+set(CMAKE_ASM_FLAGS_RELEASE        "")
diff --git a/examples/platforms/nrf528xx/nrf52833/nrf52833.cmake b/examples/platforms/nrf528xx/nrf52833/nrf52833.cmake
new file mode 100644
index 000000000..659559acd
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52833/nrf52833.cmake
@@ -0,0 +1,220 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(OT_PLATFORM_LIB "openthread-nrf52833" "openthread-nrf52833-transport" PARENT_SCOPE)
+
+if(NOT OT_CONFIG)
+    set(OT_CONFIG "${CMAKE_CURRENT_SOURCE_DIR}/nrf52833/openthread-core-nrf52833-config.h")
+    set(OT_CONFIG ${OT_CONFIG} PARENT_SCOPE)
+endif()
+
+option(OT_BOOTLOADER "OT nrf bootloader type")
+if(OT_BOOTLOADER STREQUAL "USB")
+    list(APPEND OT_PLATFORM_DEFINES "APP_USBD_NRF_DFU_TRIGGER_ENABLED=1")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52833/nrf52833_bootloader_usb.ld")
+elseif(OT_BOOTLOADER STREQUAL "UART")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52833/nrf52833_bootloader_uart.ld")
+elseif(OT_BOOTLOADER STREQUAL "BLE")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52833/nrf52833_bootloader_ble.ld")
+else()
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52833/nrf52833.ld")
+endif()
+
+list(APPEND OT_PLATFORM_DEFINES
+    "OPENTHREAD_CORE_CONFIG_PLATFORM_CHECK_FILE=\"openthread-core-nrf52833-config-check.h\""
+)
+list(APPEND OT_PUBLIC_INCLUDES
+    "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/mbedtls_plat_config"
+    "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/nrfx/mdk"
+     "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/cmsis"
+)
+
+set(OT_PLATFORM_DEFINES ${OT_PLATFORM_DEFINES} PARENT_SCOPE)
+target_compile_definitions(ot-config INTERFACE
+    "MBEDTLS_USER_CONFIG_FILE=\"nrf52833-mbedtls-config.h\""
+)
+set(OT_PUBLIC_INCLUDES ${OT_PUBLIC_INCLUDES} PARENT_SCOPE)
+
+set(COMM_FLAGS
+    -DDISABLE_CC310=1
+    -DCONFIG_GPIO_AS_PINRESET
+    -DNRF52833_XXAA
+    -DUSE_APP_CONFIG=1
+    -Wno-unused-parameter
+    -Wno-expansion-to-defined
+)
+if(OT_CFLAGS MATCHES "-pedantic-errors")
+    string(REPLACE "-pedantic-errors" "" OT_CFLAGS "${OT_CFLAGS}")
+endif()
+list(APPEND OT_PLATFORM_DEFINES "OPENTHREAD_PROJECT_CORE_CONFIG_FILE=\"${OT_CONFIG}\"")
+
+add_library(openthread-nrf52833
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+add_library(openthread-nrf52833-transport
+    ${NRF_TRANSPORT_SOURCES}
+)
+
+add_library(openthread-nrf52833-sdk
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+add_library(openthread-nrf52833-softdevice-sdk
+    ${NRF_COMM_SOURCES}
+    ${NRF_SOFTDEVICE_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+set_target_properties(openthread-nrf52833 openthread-nrf52833-transport openthread-nrf52833-sdk openthread-nrf52833-softdevice-sdk
+    PROPERTIES
+        C_STANDARD 99
+        CXX_STANDARD 11
+)
+
+target_link_libraries(openthread-nrf52833
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52833_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52833-transport
+    PUBLIC
+        ${OT_MBEDTLS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        nordicsemi-nrf52833-sdk
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52833-sdk
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52833_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52833-softdevice-sdk
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52833_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_compile_definitions(openthread-nrf52833
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52833-transport
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52833-sdk
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52833-softdevice-sdk
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_options(openthread-nrf52833
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+)
+
+target_compile_options(openthread-nrf52833-transport
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+)
+
+target_compile_options(openthread-nrf52833-sdk
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+)
+
+target_compile_options(openthread-nrf52833-softdevice-sdk
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DSOFTDEVICE_PRESENT
+        -DS140
+)
+
+target_include_directories(openthread-nrf52833
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52833
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52833-transport
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52833
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52833-sdk
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52833
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52833-softdevice-sdk
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52833
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
diff --git a/examples/platforms/nrf528xx/nrf52840/arm-none-eabi.cmake b/examples/platforms/nrf528xx/nrf52840/arm-none-eabi.cmake
new file mode 100644
index 000000000..3147abe0c
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52840/arm-none-eabi.cmake
@@ -0,0 +1,56 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(CMAKE_SYSTEM_NAME              Generic)
+set(CMAKE_SYSTEM_PROCESSOR         ARM)
+
+set(CMAKE_C_COMPILER               arm-none-eabi-gcc)
+set(CMAKE_CXX_COMPILER             arm-none-eabi-g++)
+set(CMAKE_ASM_COMPILER             arm-none-eabi-as)
+set(CMAKE_RANLIB                   arm-none-eabi-ranlib)
+
+execute_process(COMMAND ${CMAKE_CXX_COMPILER} -dumpversion OUTPUT_VARIABLE COMPILER_VERSION OUTPUT_STRIP_TRAILING_WHITESPACE)
+
+set(COMMON_C_FLAGS                 "-mcpu=cortex-m4 -mfloat-abi=hard -mfpu=fpv4-sp-d16 -mthumb -mabi=aapcs -fdata-sections -ffunction-sections")
+
+if(COMPILER_VERSION VERSION_GREATER_EQUAL 7)
+    set(COMMON_C_FLAGS             "${COMMON_C_FLAGS} -Wno-expansion-to-defined")
+endif()
+
+set(CMAKE_C_FLAGS_INIT             "${COMMON_C_FLAGS} -std=gnu99")
+set(CMAKE_CXX_FLAGS_INIT           "${COMMON_C_FLAGS} -fno-exceptions -fno-rtti")
+set(CMAKE_ASM_FLAGS_INIT           "${COMMON_C_FLAGS} -x assembler-with-cpp")
+set(CMAKE_EXE_LINKER_FLAGS_INIT    "${COMMON_C_FLAGS} -specs=nano.specs -specs=nosys.specs")
+
+set(CMAKE_C_FLAGS_DEBUG            "-Og -g")
+set(CMAKE_CXX_FLAGS_DEBUG          "-Og -g")
+set(CMAKE_ASM_FLAGS_DEBUG          "-g")
+
+set(CMAKE_C_FLAGS_RELEASE          "-Os")
+set(CMAKE_CXX_FLAGS_RELEASE        "-Os")
+set(CMAKE_ASM_FLAGS_RELEASE        "")
diff --git a/examples/platforms/nrf528xx/nrf52840/nrf52840.cmake b/examples/platforms/nrf528xx/nrf52840/nrf52840.cmake
new file mode 100644
index 000000000..fcf1a65ef
--- /dev/null
+++ b/examples/platforms/nrf528xx/nrf52840/nrf52840.cmake
@@ -0,0 +1,233 @@
+#
+#  Copyright (c) 2021, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(OT_PLATFORM_LIB "openthread-nrf52840" "openthread-nrf52840-transport" PARENT_SCOPE)
+
+if(NOT OT_CONFIG)
+    set(OT_CONFIG "${CMAKE_CURRENT_SOURCE_DIR}/nrf52840/openthread-core-nrf52840-config.h")
+    set(OT_CONFIG ${OT_CONFIG} PARENT_SCOPE)
+endif()
+
+option(OT_BOOTLOADER "OT nrf bootloader type")
+if(OT_BOOTLOADER STREQUAL "USB")
+    list(APPEND OT_PLATFORM_DEFINES "APP_USBD_NRF_DFU_TRIGGER_ENABLED=1")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52840/nrf52840_bootloader_usb.ld")
+elseif(OT_BOOTLOADER STREQUAL "UART")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52840/nrf52840_bootloader_uart.ld")
+elseif(OT_BOOTLOADER STREQUAL "BLE")
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52840/nrf52840_bootloader_ble.ld")
+else()
+    set(LD_FILE "${CMAKE_CURRENT_SOURCE_DIR}/nrf52840/nrf52840.ld")
+endif()
+
+list(APPEND OT_PLATFORM_DEFINES
+    "OPENTHREAD_CORE_CONFIG_PLATFORM_CHECK_FILE=\"openthread-core-nrf52840-config-check.h\""
+)
+if(NOT OT_EXTERNAL_MBEDTLS)
+    if(OT_MBEDTLS_THREADING)
+        list(APPEND OT_PLATFORM_DEFINES "MBEDTLS_THREADING_C")
+        list(APPEND OT_PLATFORM_DEFINES "MBEDTLS_THREADING_ALT")
+        list(APPEND OT_PUBLIC_INCLUDES
+            "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/include/software-only-threading"
+        )
+    endif()
+else()
+    list(APPEND OT_PLATFORM_DEFINES "MBEDTLS_CONFIG_FILE=\"nrf-config.h\"")
+    list(APPEND OT_PUBLIC_INCLUDES
+        "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/include"
+        "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/config"
+        "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/nrf_cc310_plat/include"
+    )
+endif()
+
+set(OT_PLATFORM_DEFINES ${OT_PLATFORM_DEFINES} PARENT_SCOPE)
+target_compile_definitions(ot-config INTERFACE
+    "MBEDTLS_USER_CONFIG_FILE=\"nrf52840-mbedtls-config.h\""
+)
+list(APPEND OT_PUBLIC_INCLUDES "${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/nrf_security/mbedtls_plat_config")
+set(OT_PUBLIC_INCLUDES ${OT_PUBLIC_INCLUDES} PARENT_SCOPE)
+
+set(COMM_FLAGS
+    -DCONFIG_GPIO_AS_PINRESET
+    -DNRF52840_XXAA
+    -DUSE_APP_CONFIG=1
+    -Wno-unused-parameter
+    -Wno-expansion-to-defined
+)
+if(OT_CFLAGS MATCHES "-pedantic-errors")
+    string(REPLACE "-pedantic-errors" "" OT_CFLAGS "${OT_CFLAGS}")
+endif()
+list(APPEND OT_PLATFORM_DEFINES "OPENTHREAD_PROJECT_CORE_CONFIG_FILE=\"${OT_CONFIG}\"")
+
+add_library(openthread-nrf52840
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+add_library(openthread-nrf52840-transport
+    ${NRF_TRANSPORT_SOURCES}
+)
+
+add_library(openthread-nrf52840-sdk
+    ${NRF_COMM_SOURCES}
+    ${NRF_SINGLEPHY_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+add_library(openthread-nrf52840-softdevice-sdk
+    ${NRF_COMM_SOURCES}
+    ${NRF_SOFTDEVICE_SOURCES}
+    $<TARGET_OBJECTS:openthread-platform-utils>
+)
+
+set_target_properties(openthread-nrf52840 openthread-nrf52840-transport openthread-nrf52840-sdk openthread-nrf52840-softdevice-sdk
+    PROPERTIES
+        C_STANDARD 99
+        CXX_STANDARD 11
+)
+
+target_link_libraries(openthread-nrf52840
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52840_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52840-transport
+    PUBLIC
+        ${OT_MBEDTLS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        nordicsemi-nrf52840-sdk
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52840-sdk
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52840_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_link_libraries(openthread-nrf52840-softdevice-sdk
+    PUBLIC
+        ${OT_MBEDTLS}
+        ${NRF52840_3RD_LIBS}
+        -T${LD_FILE}
+        -Wl,--gc-sections
+        -Wl,-Map=$<TARGET_PROPERTY:NAME>.map
+    PRIVATE
+        ot-config
+)
+
+target_compile_definitions(openthread-nrf52840
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52840-transport
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52840-sdk
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_definitions(openthread-nrf52840-softdevice-sdk
+    PUBLIC
+        ${OT_PLATFORM_DEFINES}
+)
+
+target_compile_options(openthread-nrf52840
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DPLATFORM_OPENTHREAD_VANILLA
+)
+
+target_compile_options(openthread-nrf52840-transport
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DPLATFORM_OPENTHREAD_VANILLA
+)
+
+target_compile_options(openthread-nrf52840-sdk
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+)
+
+target_compile_options(openthread-nrf52840-softdevice-sdk
+    PRIVATE
+        ${OT_CFLAGS}
+        ${COMM_FLAGS}
+        -DSOFTDEVICE_PRESENT
+        -DS140
+)
+
+target_include_directories(openthread-nrf52840
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52840
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52840-transport
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52840
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52840-sdk
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52840
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
+
+target_include_directories(openthread-nrf52840-softdevice-sdk
+    PRIVATE
+        ${CMAKE_CURRENT_SOURCE_DIR}/nrf52840
+        ${NRF_INCLUDES}
+        ${OT_PUBLIC_INCLUDES}
+)
diff --git a/script/check-arm-build-cmake b/script/check-arm-build-cmake
index 5eddf856a..9f704e40d 100755
--- a/script/check-arm-build-cmake
+++ b/script/check-arm-build-cmake
@@ -78,6 +78,24 @@ build_kw41z()
     "$(dirname "$0")"/cmake-build kw41z "${OT_COMMON_OPTIONS[@]}" "${OT_BASIC_CHECK_OPTIONS[@]}"
 }
 
+build_nrf52811()
+{
+    reset_source
+    "$(dirname "$0")"/cmake-build nrf52811 "$1" "${OT_COMMON_OPTIONS[@]}"
+}
+
+build_nrf52833()
+{
+    reset_source
+    "$(dirname "$0")"/cmake-build nrf52833 "$1" "${OT_COMMON_OPTIONS[@]}" "${OT_BASIC_CHECK_OPTIONS[@]}"
+}
+
+build_nrf52840()
+{
+    reset_source
+    "$(dirname "$0")"/cmake-build nrf52840 "$1" "${OT_COMMON_OPTIONS[@]}" "${OT_BASIC_CHECK_OPTIONS[@]}"
+}
+
 build_qpg6095()
 {
     reset_source
@@ -108,6 +126,16 @@ main()
         build_kw41z
         build_qpg6095
         build_samr21
+        # UART transport
+        build_nrf52840 UART_trans
+        # USB transport with bootloader e.g. to support PCA10059 dongle
+        build_nrf52840 USB_trans_bl
+        # SPI transport for NCP
+        build_nrf52840 SPI_trans_NCP
+        # Software cryptography
+        build_nrf52840 soft_crypto
+        # Software cryptography with threading support
+        build_nrf52840 soft_crypto_threading
         return 0
     fi
 
diff --git a/script/cmake-build b/script/cmake-build
index 71b8c1ab2..a154e6f16 100755
--- a/script/cmake-build
+++ b/script/cmake-build
@@ -42,6 +42,10 @@
 #
 #      script/cmake-build ${platform} -D${option}=OFF
 #
+#  Need to add build type when compilling nrf528xx:
+#
+#      script/cmake-build ${platform} ${nrf_build_type} -D${option}=ON -D${option}=OFF
+#
 #  Compile with the specified ninja build target:
 #
 #      OT_CMAKE_NINJA_TARGET="ot-cli-ftd" script/cmake-build ${platform}
@@ -64,7 +68,8 @@ set -euxo pipefail
 OT_CMAKE_NINJA_TARGET=${OT_CMAKE_NINJA_TARGET:-}
 
 readonly OT_SRCDIR="$(pwd)"
-readonly OT_PLATFORMS=(cc1352 cc2538 cc2650 cc2652 kw41z qpg6095 samr21 simulation posix)
+readonly OT_PLATFORMS=(cc1352 cc2538 cc2650 cc2652 kw41z nrf52811 nrf52833 nrf52840 qpg6095 samr21 simulation posix)
+readonly OT_NRF528XX_BUILD_TYPES=(UART_trans USB_trans_bl SPI_trans_NCP soft_crypto soft_crypto_threading)
 readonly OT_POSIX_SIM_COMMON_OPTIONS=(
     "-DOT_BORDER_AGENT=ON"
     "-DOT_BORDER_ROUTER=ON"
@@ -98,6 +103,33 @@ readonly OT_POSIX_SIM_COMMON_OPTIONS=(
     "-DOT_RCP_RESTORATION_MAX_COUNT=2"
 )
 
+readonly OT_nrf52811_OPTIONS=(
+    "-DOT_BORDER_ROUTER=ON"
+    "-DOT_COAP=ON"
+    "-DOT_DNS_CLIENT=ON"
+    "-DOT_LINK_RAW=ON"
+    "-DOT_MAC_FILTER=ON"
+    "-DOT_MTD_NETDIAG=ON"
+)
+
+readonly OT_nrf52833_OPTIONS=(
+    "-DOT_BORDER_AGENT=ON"
+    "-DOT_BORDER_ROUTER=ON"
+    "-DOT_COAP=ON"
+    "-DOT_COAPS=ON"
+    "-DOT_ECDSA=ON"
+    "-DOT_FULL_LOGS=ON"
+    "-DOT_IP6_FRAGM=ON"
+    "-DOT_LINK_RAW=ON"
+    "-DOT_MAC_FILTER=ON"
+    "-DOT_MTD_NETDIAG=ON"
+    "-DOT_SERVICE=ON"
+    "-DOT_SNTP_CLIENT=ON"
+    "-DOT_UDP_FORWARD=ON"
+)
+
+readonly OT_nrf52840_OPTIONS=("${OT_nrf52833_OPTIONS[@]:0}")
+
 die()
 {
     echo " ** ERROR: Openthread CMake doesn't support platform \"$1\""
@@ -132,6 +164,16 @@ main()
     fi
 
     local platform="$1"
+    # Check if the platform supports cmake.
+    echo "${OT_PLATFORMS[@]}" | grep -wq "${platform}" || die "${platform}"
+
+    local nrf_build_type=""
+    if [[ ${platform} == nrf528* ]]; then
+        nrf_build_type="$2"
+        echo "${OT_NRF528XX_BUILD_TYPES[@]}" | grep -wq "${nrf_build_type}" || die "${nrf_build_type}"
+        shift
+    fi
+
     shift
     local local_options=()
     local options=(
@@ -139,9 +181,6 @@ main()
         "-DOT_SLAAC=ON"
     )
 
-    # Check if the platform supports cmake.
-    echo "${OT_PLATFORMS[@]}" | grep -wq "${platform}" || die "${platform}"
-
     case "${platform}" in
         posix)
             local_options+=(
@@ -161,6 +200,55 @@ main()
         cc1352 | cc2538 | cc2652 | kw41z | qpg6095 | samr21)
             options+=("-DCMAKE_TOOLCHAIN_FILE=examples/platforms/${platform}/arm-none-eabi.cmake" "-DCMAKE_BUILD_TYPE=MinSizeRel")
             ;;
+        nrf52811)
+            local_options+=("${OT_nrf52811_OPTIONS[@]}" "-DCMAKE_TOOLCHAIN_FILE=examples/platforms/nrf528xx/${platform}/arm-none-eabi.cmake" "-DCMAKE_BUILD_TYPE=Release")
+            case "${nrf_build_type}" in
+                UART_trans)
+                    OT_CMAKE_NINJA_TARGET=("ot-cli-mtd" "ot-ncp-mtd" "ot-rcp")
+                    options+=("${local_options[@]}")
+                    ;;
+                SPI_trans_NCP)
+                    OT_CMAKE_NINJA_TARGET=("ot-ncp-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_NCP_SPI=ON")
+                    ;;
+            esac
+            ;;
+        nrf52833)
+            local_options+=("${OT_nrf52833_OPTIONS[@]}" "-DCMAKE_TOOLCHAIN_FILE=examples/platforms/nrf528xx/${platform}/arm-none-eabi.cmake" "-DCMAKE_BUILD_TYPE=Release")
+            case "${nrf_build_type}" in
+                UART_trans)
+                    options+=("${local_options[@]}")
+                    ;;
+                USB_trans_bl)
+                    options+=("${local_options[@]}" "-DOT_USB=ON" "-DOT_BOOTLOADER=USB")
+                    ;;
+                SPI_trans_NCP)
+                    OT_CMAKE_NINJA_TARGET=("ot-ncp-ftd" "ot-ncp-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_NCP_SPI=ON")
+                    ;;
+            esac
+            ;;
+        nrf52840)
+            local_options+=("${OT_nrf52840_OPTIONS[@]}" "-DCMAKE_TOOLCHAIN_FILE=examples/platforms/nrf528xx/${platform}/arm-none-eabi.cmake" "-DCMAKE_BUILD_TYPE=Release")
+            case "${nrf_build_type}" in
+                UART_trans)
+                    options+=("${local_options[@]}" "-DOT_EXTERNAL_MBEDTLS=nordicsemi-mbedtls")
+                    ;;
+                USB_trans_bl)
+                    options+=("${local_options[@]}" "-DOT_USB=ON" "-DOT_BOOTLOADER=USB" "-DOT_EXTERNAL_MBEDTLS=nordicsemi-mbedtls")
+                    ;;
+                SPI_trans_NCP)
+                    OT_CMAKE_NINJA_TARGET=("ot-ncp-ftd" "ot-ncp-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_NCP_SPI=ON" "-DOT_EXTERNAL_MBEDTLS=nordicsemi-mbedtls")
+                    ;;
+                soft_crypto)
+                    options+=("${local_options[@]}")
+                    ;;
+                soft_crypto_threading)
+                    options+=("${local_options[@]}" "-DOT_MBEDTLS_THREADING=ON")
+                    ;;
+            esac
+            ;;
         *)
             options+=("-DCMAKE_TOOLCHAIN_FILE=examples/platforms/${platform}/arm-none-eabi.cmake")
             ;;
diff --git a/src/ncp/CMakeLists.txt b/src/ncp/CMakeLists.txt
index 8c0134afe..86f8a54d3 100644
--- a/src/ncp/CMakeLists.txt
+++ b/src/ncp/CMakeLists.txt
@@ -51,6 +51,12 @@ set(COMMON_NCP_SOURCES
     ncp_base_ftd.cpp
     ncp_base_mtd.cpp
 )
+option(OT_NCP_SPI "enable NCP SPI support")
+if(OT_NCP_SPI)
+    target_compile_definitions(ot-config INTERFACE "OPENTHREAD_CONFIG_NCP_SPI_ENABLE=1")
+else()
+    target_compile_definitions(ot-config INTERFACE "OPENTHREAD_CONFIG_NCP_UART_ENABLE=1")
+endif()
 
 if(OT_FTD)
     include(ftd.cmake)
diff --git a/third_party/CMakeLists.txt b/third_party/CMakeLists.txt
index f777749bd..265241cbe 100644
--- a/third_party/CMakeLists.txt
+++ b/third_party/CMakeLists.txt
@@ -38,4 +38,7 @@ elseif(OT_PLATFORM STREQUAL "qpg6095")
     add_subdirectory(Qorvo)
 elseif(OT_PLATFORM STREQUAL "samr21")
     add_subdirectory(microchip)
+elseif(OT_PLATFORM MATCHES "^nrf*")
+    add_subdirectory(jlink)
+    add_subdirectory(NordicSemiconductor)
 endif()
diff --git a/third_party/NordicSemiconductor/CMakeLists.txt b/third_party/NordicSemiconductor/CMakeLists.txt
new file mode 100644
index 000000000..008b1be10
--- /dev/null
+++ b/third_party/NordicSemiconductor/CMakeLists.txt
@@ -0,0 +1,375 @@
+#
+#  Copyright (c) 2020, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+set(COMMON_INCLUDES
+    ${PROJECT_SOURCE_DIR}/include
+    ${PROJECT_SOURCE_DIR}/src
+    ${PROJECT_SOURCE_DIR}/src/core
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/fem
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/fem/three_pin_gpio
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/mac_features
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/mac_features/ack_generator
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/platform/temperature
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/platform/lp_timer
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/rsch
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/rsch/raal
+    ${CMAKE_CURRENT_SOURCE_DIR}/drivers/radio/rsch/raal/softdevice
+)
+
+set(EXAMPLE_INCLUDES
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/cmsis
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/dependencies
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/drivers/clock
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/drivers/common
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/drivers/power
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/drivers/systick
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/drivers/usbd
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/app_error
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/atfifo
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/atomic
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/block_dev
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/delay
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/usb
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/usb/config
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/usb/class/cdc
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/usb/class/cdc/acm
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/utf_converter
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/hal
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/drivers
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/drivers/include
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/mdk
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/soc
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/softdevice/s140/headers
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/softdevice/s140/headers/nrf52
+)
+
+set(COMMON_FLAG
+    -DSPIS_ENABLED=1
+    -DSPIS0_ENABLED=1
+    -DNRFX_SPIS_ENABLED=1
+    -DNRFX_SPIS0_ENABLED=1
+    -DCONFIG_GPIO_AS_PINRESET
+    -DENABLE_FEM=1
+    -DUSE_APP_CONFIG=1
+)
+
+set(COMMON_SOURCES
+    dependencies/app_util_platform.c
+    drivers/clock/nrf_drv_clock.c
+    drivers/power/nrf_drv_power.c
+    libraries/app_error/app_error.c
+    libraries/app_error/app_error_weak.c
+    libraries/utf_converter/utf.c
+    nrfx/drivers/src/nrfx_clock.c
+    nrfx/drivers/src/nrfx_nvmc.c
+    nrfx/drivers/src/nrfx_power.c
+    nrfx/drivers/src/nrfx_spis.c
+    nrfx/drivers/src/nrfx_systick.c
+    nrfx/hal/nrf_nvmc.c
+    nrfx/soc/nrfx_atomic.c
+)
+
+set(USB_SOURCES
+    nrfx/drivers/src/nrfx_usbd.c
+    libraries/atfifo/nrf_atfifo.c
+    libraries/atomic/nrf_atomic.c
+    libraries/usb/app_usbd.c
+    libraries/usb/app_usbd_core.c
+    libraries/usb/app_usbd_string_desc.c
+    libraries/usb/app_usbd_serial_num.c
+    libraries/usb/app_usbd_nrf_dfu_trigger.c
+    libraries/usb/nrf_dfu_trigger_usb.c
+    libraries/usb/class/cdc/acm/app_usbd_cdc_acm.c
+)
+
+set(RADIO_DRIVER_SOURCES
+    drivers/radio/fal/nrf_802154_fal.c
+    drivers/radio/mac_features/ack_generator/nrf_802154_ack_data.c
+    drivers/radio/mac_features/ack_generator/nrf_802154_ack_generator.c
+    drivers/radio/mac_features/ack_generator/nrf_802154_enh_ack_generator.c
+    drivers/radio/mac_features/ack_generator/nrf_802154_imm_ack_generator.c
+    drivers/radio/mac_features/nrf_802154_csma_ca.c
+    drivers/radio/mac_features/nrf_802154_delayed_trx.c
+    drivers/radio/mac_features/nrf_802154_filter.c
+    drivers/radio/mac_features/nrf_802154_frame_parser.c
+    drivers/radio/mac_features/nrf_802154_precise_ack_timeout.c
+    drivers/radio/fem/three_pin_gpio/nrf_fem_three_pin_gpio.c
+    drivers/radio/nrf_802154_core_hooks.c
+    drivers/radio/nrf_802154_core.c
+    drivers/radio/nrf_802154_critical_section.c
+    drivers/radio/nrf_802154_debug.c
+    drivers/radio/nrf_802154_pib.c
+    drivers/radio/nrf_802154_rssi.c
+    drivers/radio/nrf_802154_rx_buffer.c
+    drivers/radio/nrf_802154_timer_coord.c
+    drivers/radio/nrf_802154.c
+    drivers/radio/platform/coex/nrf_802154_wifi_coex_none.c
+    drivers/radio/platform/clock/nrf_802154_clock_ot.c
+    drivers/radio/platform/hp_timer/nrf_802154_hp_timer.c
+    drivers/radio/rsch/nrf_802154_rsch_crit_sect.c
+    drivers/radio/rsch/nrf_802154_rsch.c
+    drivers/radio/timer_scheduler/nrf_802154_timer_sched.c
+)
+
+set(SINGLE_PHY_SOURCES
+    drivers/radio/nrf_802154_notification_direct.c
+    drivers/radio/nrf_802154_priority_drop_direct.c
+    drivers/radio/nrf_802154_request_direct.c
+    drivers/radio/rsch/raal/single_phy/single_phy.c
+)
+
+set(RADIO_DRIVER_SOFTDEVICE_SOURCES
+    drivers/radio/nrf_802154_notification_swi.c
+    drivers/radio/nrf_802154_priority_drop_swi.c
+    drivers/radio/nrf_802154_request_swi.c
+    drivers/radio/nrf_802154_swi.c
+    drivers/radio/rsch/raal/softdevice/nrf_raal_softdevice.c
+)
+
+set(RADIO_DRIVER_SINGLE_PHY_SOURCES
+    drivers/radio/nrf_802154_notification_direct.c
+    drivers/radio/nrf_802154_priority_drop_direct.c
+    drivers/radio/nrf_802154_request_direct.c
+    drivers/radio/rsch/raal/single_phy/single_phy.c
+)
+
+if(OT_PLATFORM STREQUAL "nrf52811")
+    add_library(nordicsemi-nrf52811-sdk)
+    target_compile_definitions(nordicsemi-nrf52811-sdk
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52811_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -D__HEAP_SIZE=0
+            -D__STACK_SIZE=2048
+    )
+    target_include_directories(nordicsemi-nrf52811-sdk
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52811
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52811/config
+    )
+    set_property(SOURCE nrfx/mdk/gcc_startup_nrf52811.S PROPERTY LANGUAGE C)
+    target_sources(nordicsemi-nrf52811-sdk
+        PRIVATE
+            ${COMMON_SOURCES}
+            nrfx/mdk/gcc_startup_nrf52811.S
+            nrfx/mdk/system_nrf52811.c
+    )
+    target_link_libraries(nordicsemi-nrf52811-sdk PRIVATE ot-config)
+
+    add_library(nordicsemi-nrf52811-radio-driver)
+    target_compile_definitions(nordicsemi-nrf52811-radio-driver
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52811_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -D__HEAP_SIZE=0
+            -D__STACK_SIZE=2048
+            -DRAAL_SINGLE_PHY=1
+    )
+    target_include_directories(nordicsemi-nrf52811-radio-driver
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${OT_PUBLIC_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52811
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52811/config
+    )
+    target_sources(nordicsemi-nrf52811-radio-driver
+        PRIVATE
+            ${RADIO_DRIVER_SOURCES}
+            ${RADIO_DRIVER_SINGLE_PHY_SOURCES}
+    )
+elseif(OT_PLATFORM STREQUAL "nrf52833")
+    add_library(nordicsemi-nrf52833-sdk)
+    target_compile_definitions(nordicsemi-nrf52833-sdk
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52833_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+    )
+    target_include_directories(nordicsemi-nrf52833-sdk
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52833
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52833/config
+    )
+    set_property(SOURCE nrfx/mdk/gcc_startup_nrf52833.S PROPERTY LANGUAGE C)
+    target_sources(nordicsemi-nrf52833-sdk
+        PRIVATE
+            ${COMMON_SOURCES}
+            ${USB_SOURCES}
+            nrfx/mdk/gcc_startup_nrf52833.S
+            nrfx/mdk/system_nrf52833.c
+    )
+    target_link_libraries(nordicsemi-nrf52833-sdk PRIVATE ot-config)
+
+    add_library(nordicsemi-nrf52833-radio-driver)
+    target_compile_definitions(nordicsemi-nrf52833-radio-driver
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52833_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -DRAAL_SINGLE_PHY=1
+    )
+    target_include_directories(nordicsemi-nrf52833-radio-driver
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${OT_PUBLIC_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52833
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52833/config
+    )
+    target_sources(nordicsemi-nrf52833-radio-driver
+        PRIVATE
+            ${RADIO_DRIVER_SOURCES}
+            ${RADIO_DRIVER_SINGLE_PHY_SOURCES}
+    )
+    add_library(nordicsemi-nrf52833-radio-driver-softdevice)
+    target_compile_definitions(nordicsemi-nrf52833-radio-driver-softdevice
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52833_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -DRAAL_SINGLE_PHY=1
+            -DSOFTDEVICE_PRESENT
+            -DS140
+            -DRAAL_SOFTDEVICE=1
+    )
+    target_include_directories(nordicsemi-nrf52833-radio-driver-softdevice
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${OT_PUBLIC_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52833
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52833/config
+    )
+    target_sources(nordicsemi-nrf52833-radio-driver-softdevice
+        PRIVATE
+            ${RADIO_DRIVER_SOURCES}
+            ${RADIO_DRIVER_SINGLE_PHY_SOURCES}
+    )
+elseif(OT_PLATFORM STREQUAL "nrf52840")
+    add_library(nordicsemi-nrf52840-sdk)
+    target_compile_definitions(nordicsemi-nrf52840-sdk
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52840_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+    )
+    target_include_directories(nordicsemi-nrf52840-sdk
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52840/
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52840/config
+    )
+    set_property(SOURCE nrfx/mdk/gcc_startup_nrf52840.S PROPERTY LANGUAGE C)
+    target_sources(nordicsemi-nrf52840-sdk
+        PRIVATE
+            ${COMMON_SOURCES}
+            ${USB_SOURCES}
+            nrfx/mdk/gcc_startup_nrf52840.S
+            nrfx/mdk/system_nrf52840.c
+    )
+    target_link_libraries(nordicsemi-nrf52840-sdk PRIVATE ot-config)
+
+    add_library(nordicsemi-nrf52840-radio-driver)
+    target_compile_definitions(nordicsemi-nrf52840-radio-driver
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52840_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -DRAAL_SINGLE_PHY=1
+    )
+    target_include_directories(nordicsemi-nrf52840-radio-driver
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${OT_PUBLIC_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52840/
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52840/config
+    )
+    target_sources(nordicsemi-nrf52840-radio-driver
+        PRIVATE
+            ${RADIO_DRIVER_SOURCES}
+            ${RADIO_DRIVER_SINGLE_PHY_SOURCES}
+    )
+
+    add_library(nordicsemi-nrf52840-radio-driver-softdevice)
+    target_compile_definitions(nordicsemi-nrf52840-radio-driver-softdevice
+        PRIVATE
+            ${COMMON_FLAG}
+            -DNRF52840_XXAA
+            -DNRF_802154_PROJECT_CONFIG=\"platform-config.h\"
+            -DRAAL_SINGLE_PHY=1
+            -DSOFTDEVICE_PRESENT
+            -DS140
+            -DRAAL_SOFTDEVICE=1
+    )
+    target_include_directories(nordicsemi-nrf52840-radio-driver-softdevice
+        PUBLIC
+            ${COMMON_INCLUDES}
+            ${EXAMPLE_INCLUDES}
+            ${OT_PUBLIC_INCLUDES}
+            ${PROJECT_SOURCE_DIR}/examples/platforms/nrf528xx/nrf52840/
+            ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/nrf52840/config
+    )
+    target_sources(nordicsemi-nrf52840-radio-driver-softdevice
+        PRIVATE
+            ${RADIO_DRIVER_SOURCES}
+            ${RADIO_DRIVER_SINGLE_PHY_SOURCES}
+    )
+else()
+    message(FATAL_ERROR "Platform unknown: ${OT_PLATFORM}")
+endif()
+
+add_library(nordicsemi-mbedtls INTERFACE)
+
+target_link_libraries(nordicsemi-mbedtls
+    INTERFACE
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedcrypto_shared.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedtls_tls_vanilla.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedtls_x509_vanilla.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedcrypto_cc3xx.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libnrf_cc310_platform_0.9.4.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedcrypto_oberon.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedtls_base_vanilla.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedcrypto_cc3xx.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedtls_base_vanilla.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libmbedcrypto_shared.a
+        ${CMAKE_CURRENT_SOURCE_DIR}/libraries/nrf_security/lib/libnrf_cc310_platform_0.9.4.a
+)
+
diff --git a/third_party/jlink/CMakeLists.txt b/third_party/jlink/CMakeLists.txt
new file mode 100644
index 000000000..f3e22bd39
--- /dev/null
+++ b/third_party/jlink/CMakeLists.txt
@@ -0,0 +1,61 @@
+#
+#  Copyright (c) 2020, The OpenThread Authors.
+#  All rights reserved.
+#
+#  Redistribution and use in source and binary forms, with or without
+#  modification, are permitted provided that the following conditions are met:
+#  1. Redistributions of source code must retain the above copyright
+#     notice, this list of conditions and the following disclaimer.
+#  2. Redistributions in binary form must reproduce the above copyright
+#     notice, this list of conditions and the following disclaimer in the
+#     documentation and/or other materials provided with the distribution.
+#  3. Neither the name of the copyright holder nor the
+#     names of its contributors may be used to endorse or promote products
+#     derived from this software without specific prior written permission.
+#
+#  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+#  AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+#  IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
+#  ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
+#  LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
+#  CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
+#  SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
+#  INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
+#  CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
+#  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
+#  POSSIBILITY OF SUCH DAMAGE.
+#
+
+string(REPLACE "-Wundef" "" OT_CFLAGS "${OT_CFLAGS}")
+add_library(jlinkrtt
+    SEGGER_RTT_V640/RTT/SEGGER_RTT.c
+)
+
+if(OT_PLATFORM STREQUAL "nrf52811")
+    target_compile_options(jlinkrtt PRIVATE
+        -DNRF52811_XXAA
+    )
+elseif(OT_PLATFORM STREQUAL "nrf52833")
+    target_compile_options(jlinkrtt PRIVATE
+        -DNRF52833_XXAA
+    )
+else()
+    target_compile_options(jlinkrtt PRIVATE
+        -DNRF52840_XXAA
+    )
+endif()
+
+target_compile_options(jlinkrtt PRIVATE
+    -DSEGGER_RTT_CONFIG_H=\"${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/segger_rtt/SEGGER_RTT_Conf.h\"
+    -DUSE_APP_CONFIG=1
+)
+
+target_include_directories(jlinkrtt PRIVATE
+    ${PROJECT_SOURCE_DIR}/include
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/cmsis
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/config/${OT_PLATFORM}/config
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/dependencies
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/libraries/app_error
+    ${PROJECT_SOURCE_DIR}/third_party/NordicSemiconductor/nrfx/mdk
+)