diff --git a/src/cli/cli.cpp b/src/cli/cli.cpp
index df6be4601..f7bf7635e 100644
--- a/src/cli/cli.cpp
+++ b/src/cli/cli.cpp
@@ -2278,7 +2278,7 @@ exit:
     return error;
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
 
 otError Interpreter::ProcessMlr(uint8_t aArgsLength, char *aArgs[])
 {
@@ -2363,7 +2363,7 @@ void Interpreter::HandleMlrRegResult(otError             aError,
     OutputResult(aError);
 }
 
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#endif // (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
 
 otError Interpreter::ProcessMode(uint8_t aArgsLength, char *aArgs[])
 {
diff --git a/src/cli/cli.hpp b/src/cli/cli.hpp
index ae171177f..978fa9dd7 100644
--- a/src/cli/cli.hpp
+++ b/src/cli/cli.hpp
@@ -393,7 +393,7 @@ private:
 
     otError ParseLinkMetricsFlags(otLinkMetrics &aLinkMetrics, char *aFlags);
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     otError ProcessMlr(uint8_t aArgsLength, char *aArgs[]);
 
     otError ProcessMlrReg(uint8_t aArgsLength, char *aArgs[]);
@@ -672,7 +672,7 @@ private:
         {"macfilter", &Interpreter::ProcessMacFilter},
 #endif
         {"masterkey", &Interpreter::ProcessMasterKey},
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
         {"mlr", &Interpreter::ProcessMlr},
 #endif
         {"mode", &Interpreter::ProcessMode},
diff --git a/src/core/api/ip6_api.cpp b/src/core/api/ip6_api.cpp
index a24890d56..65f2ad4bf 100644
--- a/src/core/api/ip6_api.cpp
+++ b/src/core/api/ip6_api.cpp
@@ -258,7 +258,7 @@ exit:
     return error;
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
 otError otIp6RegisterMulticastListeners(otInstance *                            aInstance,
                                         const otIp6Address *                    aAddresses,
                                         uint8_t                                 aAddressNum,
diff --git a/src/core/backbone_router/bbr_leader.cpp b/src/core/backbone_router/bbr_leader.cpp
index cf5f11e08..806f20034 100644
--- a/src/core/backbone_router/bbr_leader.cpp
+++ b/src/core/backbone_router/bbr_leader.cpp
@@ -242,11 +242,11 @@ void Leader::UpdateBackboneRouterPrimary(void)
     Get<BackboneRouter::Local>().HandleBackboneRouterPrimaryUpdate(state, mConfig);
 #endif
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
     Get<MlrManager>().HandleBackboneRouterPrimaryUpdate(state, mConfig);
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     Get<DuaManager>().HandleBackboneRouterPrimaryUpdate(state, mConfig);
 #endif
 }
@@ -307,7 +307,7 @@ void Leader::UpdateDomainPrefixConfig(void)
 #endif
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     Get<DuaManager>().HandleDomainPrefixUpdate(state);
 #endif
 }
diff --git a/src/core/common/instance.hpp b/src/core/common/instance.hpp
index 031f501ff..9d9ee552f 100644
--- a/src/core/common/instance.hpp
+++ b/src/core/common/instance.hpp
@@ -542,7 +542,7 @@ template <> inline DataPollHandler &Instance::Get(void)
     return mThreadNetif.mMeshForwarder.mIndirectSender.mDataPollHandler;
 }
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 template <> inline CslTxScheduler &Instance::Get(void)
 {
     return mThreadNetif.mMeshForwarder.mIndirectSender.mCslTxScheduler;
@@ -798,14 +798,14 @@ template <> inline BackboneRouter::BackboneTmfAgent &Instance::Get(void)
 }
 #endif
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 template <> inline MlrManager &Instance::Get(void)
 {
     return mThreadNetif.mMlrManager;
 }
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
 template <> inline DuaManager &Instance::Get(void)
 {
     return mThreadNetif.mDuaManager;
diff --git a/src/core/common/notifier.cpp b/src/core/common/notifier.cpp
index 79282ba90..8b0be4b70 100644
--- a/src/core/common/notifier.cpp
+++ b/src/core/common/notifier.cpp
@@ -158,10 +158,10 @@ void Notifier::EmitEvents(void)
 #if OPENTHREAD_CONFIG_BORDER_AGENT_ENABLE
     Get<MeshCoP::BorderAgent>().HandleNotifierEvents(events);
 #endif
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
     Get<MlrManager>().HandleNotifierEvents(events);
 #endif
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     Get<DuaManager>().HandleNotifierEvents(events);
 #endif
 #if OPENTHREAD_CONFIG_TIME_SYNC_ENABLE
diff --git a/src/core/common/time_ticker.cpp b/src/core/common/time_ticker.cpp
index dfe2deb62..10461d098 100644
--- a/src/core/common/time_ticker.cpp
+++ b/src/core/common/time_ticker.cpp
@@ -109,14 +109,14 @@ void TimeTicker::HandleTimer(void)
     }
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     if (mReceivers & Mask(kDuaManager))
     {
         Get<DuaManager>().HandleTimeTick();
     }
 #endif
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
     if (mReceivers & Mask(kMlrManager))
     {
         Get<MlrManager>().HandleTimeTick();
diff --git a/src/core/config/mac.h b/src/core/config/mac.h
index 7a87e68c7..7ab7b87b8 100644
--- a/src/core/config/mac.h
+++ b/src/core/config/mac.h
@@ -326,13 +326,14 @@
 #endif
 
 /**
+ * @def OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
  *
- * This setting configures the CSL transmitter feature in Thread 1.2.
- * This is compulsory for 1.2 FTD.
+ * Define to 1 to enable csl transmitter logic.
  *
  */
-#define OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE \
-    (OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2) && (OPENTHREAD_FTD || OPENTHREAD_RADIO)
+#ifndef OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#define OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE (OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2)
+#endif
 
 /**
  * @def OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
diff --git a/src/core/config/openthread-core-config-check.h b/src/core/config/openthread-core-config-check.h
index d22570850..0b8253191 100644
--- a/src/core/config/openthread-core-config-check.h
+++ b/src/core/config/openthread-core-config-check.h
@@ -511,9 +511,6 @@
 #if (OPENTHREAD_CONFIG_THREAD_VERSION < OT_THREAD_VERSION_1_2)
 #error "Thread 1.2 or higher version is required for OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE"
 #endif
-#if (!OPENTHREAD_FTD && !OPENTHREAD_RADIO)
-#error "FTD or RADIO is required for OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE"
-#endif
 #endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
 #if OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
diff --git a/src/core/config/tmf.h b/src/core/config/tmf.h
index e3f8a2849..7959f37c8 100644
--- a/src/core/config/tmf.h
+++ b/src/core/config/tmf.h
@@ -180,8 +180,7 @@
  *
  */
 #ifndef OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
-#define OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE \
-    ((OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2) && OPENTHREAD_FTD)
+#define OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE (OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2)
 #endif
 
 #if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE && OPENTHREAD_CONFIG_THREAD_VERSION < OT_THREAD_VERSION_1_2
@@ -194,8 +193,7 @@
  *
  */
 #ifndef OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
-#define OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE \
-    ((OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2) && OPENTHREAD_FTD)
+#define OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE (OPENTHREAD_CONFIG_THREAD_VERSION >= OT_THREAD_VERSION_1_2)
 #endif
 
 #if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_THREAD_VERSION < OT_THREAD_VERSION_1_2
diff --git a/src/core/mac/data_poll_handler.hpp b/src/core/mac/data_poll_handler.hpp
index 730494917..d1e140809 100644
--- a/src/core/mac/data_poll_handler.hpp
+++ b/src/core/mac/data_poll_handler.hpp
@@ -90,7 +90,7 @@ public:
     class ChildInfo
     {
         friend class DataPollHandler;
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         friend class CslTxScheduler;
 #endif
 
diff --git a/src/core/mac/mac.cpp b/src/core/mac/mac.cpp
index c5e873a88..f98f45aa4 100644
--- a/src/core/mac/mac.cpp
+++ b/src/core/mac/mac.cpp
@@ -109,7 +109,7 @@ Mac::Mac(Instance &aInstance)
 #if OPENTHREAD_FTD
     , mMaxFrameRetriesIndirect(kDefaultMaxFrameRetriesIndirect)
 #endif
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     , mCslTxFireTime(TimeMilli::kMaxDuration)
 #endif
     , mActiveScanHandler(nullptr) // Initialize `mActiveScanHandler` and `mEnergyScanHandler` union
@@ -204,7 +204,7 @@ bool Mac::IsInTransmitState(void) const
     case kOperationTransmitDataDirect:
 #if OPENTHREAD_FTD
     case kOperationTransmitDataIndirect:
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
 #endif
 #endif
@@ -578,7 +578,7 @@ exit:
     return;
 }
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 void Mac::RequestCslFrameTransmission(uint32_t aDelay)
 {
     VerifyOrExit(mEnabled);
@@ -652,7 +652,7 @@ void Mac::UpdateIdleMode(void)
         }
 #endif
     }
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     else if (mPendingTransmitDataCsl)
     {
         mTimer.FireAt(mCslTxFireTime);
@@ -724,7 +724,7 @@ void Mac::StartOperation(Operation aOperation)
         mPendingTransmitDataIndirect = true;
         break;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
         mPendingTransmitDataCsl = true;
         break;
@@ -769,7 +769,7 @@ void Mac::PerformNextOperation(void)
         mPendingTransmitDataDirect = false;
 #if OPENTHREAD_FTD
         mPendingTransmitDataIndirect = false;
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         mPendingTransmitDataCsl = false;
 #endif
 #endif
@@ -790,7 +790,7 @@ void Mac::PerformNextOperation(void)
         mPendingWaitingForData = false;
         mOperation             = kOperationWaitingForData;
     }
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     else if (mPendingTransmitDataCsl && TimerMilli::GetNow() >= mCslTxFireTime)
     {
         mPendingTransmitDataCsl = false;
@@ -867,7 +867,7 @@ void Mac::PerformNextOperation(void)
     case kOperationTransmitDataDirect:
 #if OPENTHREAD_FTD
     case kOperationTransmitDataIndirect:
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
 #endif
 #endif
@@ -1094,7 +1094,7 @@ void Mac::BeginTransmit(void)
     VerifyOrExit(IsEnabled(), error = OT_ERROR_ABORT);
     sendFrame.SetIsARetransmission(false);
     sendFrame.SetIsSecurityProcessed(false);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     sendFrame.SetTxDelay(0);
     sendFrame.SetTxDelayBaseTime(0);
 #endif
@@ -1149,7 +1149,7 @@ void Mac::BeginTransmit(void)
         }
         break;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
         sendFrame.SetMaxCsmaBackoffs(kMaxCsmaBackoffsCsl);
         sendFrame.SetMaxFrameRetries(kMaxFrameRetriesCsl);
@@ -1314,7 +1314,7 @@ void Mac::RecordFrameTransmitStatus(const TxFrame &aFrame,
 #if OPENTHREAD_FTD
         if (aAckFrame->GetVersion() == Frame::kFcfFrameVersion2015)
         {
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
             ProcessCsl(*aAckFrame, dstAddr);
 #endif
         }
@@ -1459,7 +1459,7 @@ void Mac::HandleTransmitDone(TxFrame &aFrame, RxFrame *aAckFrame, otError aError
         break;
 
 #if OPENTHREAD_FTD
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
         mCounters.mTxData++;
 
@@ -1539,7 +1539,7 @@ void Mac::HandleTimer(void)
             }
 #endif
         }
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         else if (mPendingTransmitDataCsl)
         {
             PerformNextOperation();
@@ -1903,7 +1903,7 @@ void Mac::HandleReceivedFrame(RxFrame *aFrame, otError aError)
         ExitNow();
     }
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     if (aFrame->GetVersion() == Frame::kFcfFrameVersion2015)
     {
         ProcessCsl(*aFrame, srcaddr);
@@ -2199,7 +2199,7 @@ const char *Mac::OperationToString(Operation aOperation)
         retval = "TransmitDataIndirect";
         break;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kOperationTransmitDataCsl:
         retval = "TransmitDataCsl";
         break;
@@ -2352,7 +2352,7 @@ bool Mac::IsCslEnabled(void) const
 
 #endif // OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 void Mac::ProcessCsl(const RxFrame &aFrame, const Address &aSrcAddr)
 {
     const uint8_t *cur   = aFrame.GetHeaderIe(Frame::kHeaderIeCsl);
@@ -2378,7 +2378,7 @@ void Mac::ProcessCsl(const RxFrame &aFrame, const Address &aSrcAddr)
 exit:
     return;
 }
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
 #if OPENTHREAD_CONFIG_MAC_HEADER_IE_SUPPORT
 otError Mac::AppendHeaderIe(bool aIsTimeSync, TxFrame &aFrame) const
@@ -2463,7 +2463,7 @@ void Mac::UpdateFrameControlField(const Neighbor *aNeighbor, bool aIsTimeSync, u
     }
     else
 #endif
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         if (aNeighbor != nullptr && !Mle::MleRouter::IsActiveRouter(aNeighbor->GetRloc16()) &&
             static_cast<const Child *>(aNeighbor)->IsCslSynchronized())
     {
diff --git a/src/core/mac/mac.hpp b/src/core/mac/mac.hpp
index c02b4646d..22cf65738 100644
--- a/src/core/mac/mac.hpp
+++ b/src/core/mac/mac.hpp
@@ -219,7 +219,7 @@ public:
      */
     void RequestIndirectFrameTransmission(void);
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     /**
      * This method requests `Mac` to start a CSL tx operation after a delay of @p aDelay time.
      *
@@ -790,7 +790,7 @@ private:
         kOperationTransmitDataDirect,
 #if OPENTHREAD_FTD
         kOperationTransmitDataIndirect,
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         kOperationTransmitDataCsl,
 #endif
 #endif
@@ -859,7 +859,7 @@ private:
     uint8_t GetTimeIeOffset(const Frame &aFrame);
 #endif
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     void ProcessCsl(const RxFrame &aFrame, const Address &aSrcAddr);
 #endif
     static const char *OperationToString(Operation aOperation);
@@ -878,7 +878,7 @@ private:
 #if OPENTHREAD_FTD
     bool mPendingTransmitDataIndirect : 1;
 #endif
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     bool mPendingTransmitDataCsl : 1;
 #endif
     bool mPendingTransmitPoll : 1;
@@ -914,7 +914,7 @@ private:
 #if OPENTHREAD_FTD
     uint8_t mMaxFrameRetriesIndirect;
 #endif
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     TimeMilli mCslTxFireTime;
 #endif
 
diff --git a/src/core/mac/sub_mac.cpp b/src/core/mac/sub_mac.cpp
index d44f234c7..dd27e7146 100644
--- a/src/core/mac/sub_mac.cpp
+++ b/src/core/mac/sub_mac.cpp
@@ -283,7 +283,7 @@ otError SubMac::Send(void)
     {
     case kStateDisabled:
     case kStateCsmaBackoff:
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kStateCslTransmit:
 #endif
     case kStateTransmit:
@@ -349,7 +349,7 @@ void SubMac::StartCsmaBackoff(void)
     uint32_t backoff;
     uint32_t backoffExponent = kMinBE + mTransmitRetries + mCsmaBackoffs;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     if (mTransmitFrame.mInfo.mTxInfo.mTxDelay != 0)
     {
         SetState(kStateCslTransmit);
@@ -375,7 +375,7 @@ void SubMac::StartCsmaBackoff(void)
 
         ExitNow();
     }
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     SetState(kStateCsmaBackoff);
 
     VerifyOrExit(ShouldHandleCsmaBackOff(), BeginTransmit());
@@ -413,7 +413,7 @@ void SubMac::BeginTransmit(void)
 
     OT_UNUSED_VARIABLE(error);
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     VerifyOrExit(mState == kStateCsmaBackoff || mState == kStateCslTransmit);
 #else
     VerifyOrExit(mState == kStateCsmaBackoff);
@@ -583,7 +583,7 @@ otError SubMac::EnergyScan(uint8_t aScanChannel, uint16_t aScanDuration)
     case kStateDisabled:
     case kStateCsmaBackoff:
     case kStateTransmit:
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kStateCslTransmit:
 #endif
     case kStateEnergyScan:
@@ -664,7 +664,7 @@ void SubMac::HandleTimer(void)
 {
     switch (mState)
     {
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kStateCslTransmit:
         BeginTransmit();
         break;
@@ -881,7 +881,7 @@ const char *SubMac::StateToString(State aState)
     case kStateEnergyScan:
         str = "EnergyScan";
         break;
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     case kStateCslTransmit:
         str = "CslTransmit";
         break;
diff --git a/src/core/mac/sub_mac.hpp b/src/core/mac/sub_mac.hpp
index ff9646d9b..8ab30ea27 100644
--- a/src/core/mac/sub_mac.hpp
+++ b/src/core/mac/sub_mac.hpp
@@ -522,7 +522,7 @@ private:
         kStateCsmaBackoff, ///< CSMA backoff before transmission.
         kStateTransmit,    ///< Radio is transmitting.
         kStateEnergyScan,  ///< Energy scan.
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         kStateCslTransmit, ///< CSL transmission.
 #endif
 #if OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
diff --git a/src/core/thread/csl_tx_scheduler.cpp b/src/core/thread/csl_tx_scheduler.cpp
index 7216f082d..065ab1994 100644
--- a/src/core/thread/csl_tx_scheduler.cpp
+++ b/src/core/thread/csl_tx_scheduler.cpp
@@ -28,7 +28,7 @@
 
 #include "csl_tx_scheduler.hpp"
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
 #include "common/locator-getters.hpp"
 #include "common/logging.hpp"
@@ -287,4 +287,4 @@ exit:
 
 } // namespace ot
 
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
diff --git a/src/core/thread/csl_tx_scheduler.hpp b/src/core/thread/csl_tx_scheduler.hpp
index d7509bd09..777f9d9f5 100644
--- a/src/core/thread/csl_tx_scheduler.hpp
+++ b/src/core/thread/csl_tx_scheduler.hpp
@@ -50,7 +50,7 @@ namespace ot {
  * @{
  */
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
 class Child;
 
@@ -208,7 +208,7 @@ private:
     Callbacks               mCallbacks;
 };
 
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
 /**
  * @}
diff --git a/src/core/thread/dua_manager.cpp b/src/core/thread/dua_manager.cpp
index 04ea7ee34..5941bda7f 100644
--- a/src/core/thread/dua_manager.cpp
+++ b/src/core/thread/dua_manager.cpp
@@ -33,7 +33,7 @@
 
 #include "dua_manager.hpp"
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
 
 #include "common/code_utils.hpp"
 #include "common/instance.hpp"
@@ -59,7 +59,7 @@ DuaManager::DuaManager(Instance &aInstance)
     , mDadCounter(0)
     , mLastRegistrationTime(0)
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     , mChildIndexDuaRegistering(0)
     , mRegisterCurrentChildIndex(false)
 #endif
@@ -71,7 +71,7 @@ DuaManager::DuaManager(Instance &aInstance)
     mFixedDuaInterfaceIdentifier.Clear();
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     mChildDuaMask.Clear();
     mChildDuaRegisteredMask.Clear();
 #endif
@@ -93,7 +93,7 @@ void DuaManager::HandleDomainPrefixUpdate(BackboneRouter::Leader::DomainPrefixSt
         RemoveDomainUnicastAddress();
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
         if (mChildDuaMask.HasAny())
         {
             mChildDuaMask.Clear();
@@ -379,7 +379,7 @@ void DuaManager::HandleTimeTick(void)
         }
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
         mChildDuaRegisteredMask.Clear();
 #endif
         attempt = true;
@@ -421,14 +421,14 @@ void DuaManager::PerformNextRegistration(void)
 
     // Only send DUA.req when necessary
 #if OPENTHREAD_CONFIG_DUA_ENABLE
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     VerifyOrExit(mle.IsRouterOrLeader() || !mle.IsExpectedToBecomeRouter(), error = OT_ERROR_INVALID_STATE);
     VerifyOrExit((mDuaState == kToRegister && mDelay.mFields.mRegistrationDelay == 0) ||
                      (mChildDuaMask.HasAny() && mChildDuaMask != mChildDuaRegisteredMask),
                  error = OT_ERROR_NOT_FOUND);
 #else
     VerifyOrExit(mDuaState == kToRegister && mDelay.mFields.mRegistrationDelay == 0, error = OT_ERROR_NOT_FOUND);
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
 
     VerifyOrExit(mle.IsFullThreadDevice() || mle.GetParent().IsThreadVersion1p1(), error = OT_ERROR_INVALID_STATE);
 #endif // OPENTHREAD_CONFIG_DUA_ENABLE
@@ -451,7 +451,7 @@ void DuaManager::PerformNextRegistration(void)
     else
 #endif // OPENTHREAD_CONFIG_DUA_ENABLE
     {
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
         uint32_t            lastTransactionTime;
         const Ip6::Address *duaPtr = nullptr;
         Child *             child  = nullptr;
@@ -481,7 +481,7 @@ void DuaManager::PerformNextRegistration(void)
 
         lastTransactionTime = Time::MsecToSec(TimerMilli::GetNow() - child->GetLastHeard());
         SuccessOrExit(error = Tlv::Append<ThreadLastTransactionTimeTlv>(*message, lastTransactionTime));
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     }
 
     if (!mle.IsFullThreadDevice() && mle.GetParent().IsThreadVersion1p1())
@@ -616,7 +616,7 @@ otError DuaManager::ProcessDuaResponse(Coap::Message &aMessage)
     }
     else
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     {
         Child *child = Get<ChildTable>().GetChildAtIndex(mChildIndexDuaRegistering);
 
@@ -649,14 +649,14 @@ otError DuaManager::ProcessDuaResponse(Coap::Message &aMessage)
             break;
         }
     }
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
 
 exit:
     UpdateTimeTickerRegistration();
     return error;
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
 void DuaManager::SendAddressNotification(Ip6::Address &             aAddress,
                                          ThreadStatusTlv::DuaStatus aStatus,
                                          const Child &              aChild)
@@ -730,8 +730,8 @@ void DuaManager::UpdateChildDomainUnicastAddress(const Child &aChild, Mle::Child
 
     return;
 }
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
 
 } // namespace ot
 
-#endif // OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
diff --git a/src/core/thread/dua_manager.hpp b/src/core/thread/dua_manager.hpp
index 255c056b4..be31a2d42 100644
--- a/src/core/thread/dua_manager.hpp
+++ b/src/core/thread/dua_manager.hpp
@@ -36,7 +36,7 @@
 
 #include "openthread-core-config.h"
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
 
 #include "backbone_router/bbr_leader.hpp"
 #include "coap/coap.hpp"
@@ -162,7 +162,7 @@ public:
     void NotifyDuplicateDomainUnicastAddress(void);
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     void UpdateChildDomainUnicastAddress(const Child &aChild, Mle::ChildDuaState aState);
 #endif
 
@@ -181,7 +181,7 @@ private:
     void UpdateRegistrationDelay(uint8_t aDelay);
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     void SendAddressNotification(Ip6::Address &aAddress, ThreadStatusTlv::DuaStatus aStatus, const Child &aChild);
 #endif
 
@@ -251,7 +251,7 @@ private:
         uint32_t mValue; ///< Non-zero indicates timer should start.
     } mDelay;
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     // TODO: (DUA) may re-evaluate the alternative option of distributing the flags into the child table:
     //       - Child class itself have some padding - may save some RAM
     //       - Avoid cross reference between a bit-vector and the child entry
@@ -264,5 +264,5 @@ private:
 
 } // namespace ot
 
-#endif // OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#endif // OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
 #endif // DUA_MANAGER_HPP_
diff --git a/src/core/thread/indirect_sender.cpp b/src/core/thread/indirect_sender.cpp
index dd0375433..1ad113c32 100644
--- a/src/core/thread/indirect_sender.cpp
+++ b/src/core/thread/indirect_sender.cpp
@@ -65,7 +65,7 @@ IndirectSender::IndirectSender(Instance &aInstance)
     , mEnabled(false)
     , mSourceMatchController(aInstance)
     , mDataPollHandler(aInstance)
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     , mCslTxScheduler(aInstance)
 #endif
 {
@@ -82,7 +82,7 @@ void IndirectSender::Stop(void)
     }
 
     mDataPollHandler.Clear();
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     mCslTxScheduler.Clear();
 #endif
 
@@ -163,7 +163,7 @@ void IndirectSender::ClearAllMessagesForSleepyChild(Child &aChild)
     mSourceMatchController.ResetMessageCount(aChild);
 
     mDataPollHandler.RequestFrameChange(DataPollHandler::kPurgeFrame, aChild);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     mCslTxScheduler.Update();
 #endif
 
@@ -208,7 +208,7 @@ void IndirectSender::HandleChildModeChange(Child &aChild, Mle::DeviceMode aOldMo
         mSourceMatchController.ResetMessageCount(aChild);
 
         mDataPollHandler.RequestFrameChange(DataPollHandler::kPurgeFrame, aChild);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         mCslTxScheduler.Update();
 #endif
     }
@@ -263,7 +263,7 @@ void IndirectSender::RequestMessageUpdate(Child &aChild)
 
         aChild.SetWaitingForMessageUpdate(true);
         mDataPollHandler.RequestFrameChange(DataPollHandler::kPurgeFrame, aChild);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         mCslTxScheduler.Update();
 #endif
 
@@ -295,7 +295,7 @@ void IndirectSender::RequestMessageUpdate(Child &aChild)
 
     aChild.SetWaitingForMessageUpdate(true);
     mDataPollHandler.RequestFrameChange(DataPollHandler::kReplaceFrame, aChild);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     mCslTxScheduler.Update();
 #endif
 
@@ -321,7 +321,7 @@ void IndirectSender::UpdateIndirectMessage(Child &aChild)
     aChild.SetIndirectFragmentOffset(0);
     aChild.SetIndirectTxSuccess(true);
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     mCslTxScheduler.Update();
 #endif
 
@@ -463,7 +463,7 @@ void IndirectSender::HandleSentFrameToChild(const Mac::TxFrame &aFrame,
     {
         aChild.SetIndirectFragmentOffset(nextOffset);
         mDataPollHandler.HandleNewFrame(aChild);
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         mCslTxScheduler.Update();
 #endif
         ExitNow();
diff --git a/src/core/thread/indirect_sender.hpp b/src/core/thread/indirect_sender.hpp
index 95bd141b4..f0bca7620 100644
--- a/src/core/thread/indirect_sender.hpp
+++ b/src/core/thread/indirect_sender.hpp
@@ -67,7 +67,7 @@ class IndirectSender : public InstanceLocator, public IndirectSenderBase, privat
 {
     friend class Instance;
     friend class DataPollHandler::Callbacks;
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     friend class CslTxScheduler::Callbacks;
 #endif
 
@@ -228,7 +228,7 @@ private:
     bool                  mEnabled;
     SourceMatchController mSourceMatchController;
     DataPollHandler       mDataPollHandler;
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     CslTxScheduler mCslTxScheduler;
 #endif
 };
diff --git a/src/core/thread/mle.hpp b/src/core/thread/mle.hpp
index 012eb00cc..2bec7b9d3 100644
--- a/src/core/thread/mle.hpp
+++ b/src/core/thread/mle.hpp
@@ -1241,7 +1241,7 @@ protected:
     otError AppendXtalAccuracy(Message &aMessage);
 #endif // OPENTHREAD_CONFIG_TIME_SYNC_ENABLE
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE || OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
+#if (!OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE) || OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
     /**
      * This method appends a CSL Channel TLV to a message.
      *
@@ -1263,7 +1263,7 @@ protected:
      *
      */
     otError AppendCslTimeout(Message &aMessage);
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE || OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
+#endif // (!OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE) || OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE
 
     /**
      * This method appends a Active Timestamp TLV to a message.
diff --git a/src/core/thread/mle_router.cpp b/src/core/thread/mle_router.cpp
index 71073a3c3..96839289f 100644
--- a/src/core/thread/mle_router.cpp
+++ b/src/core/thread/mle_router.cpp
@@ -1779,7 +1779,7 @@ void MleRouter::HandleTimeTick(void)
             OT_UNREACHABLE_CODE(break);
         }
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         if (child.IsCslSynchronized() &&
             TimerMilli::GetNow() - child.GetCslLastHeard() >= Time::SecToMsec(child.GetCslTimeout()))
         {
@@ -1969,13 +1969,13 @@ otError MleRouter::UpdateChildAddresses(const Message &aMessage, uint16_t aOffse
     uint8_t                  storedCount     = 0;
     uint16_t                 offset          = 0;
     uint16_t                 end             = 0;
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     Ip6::Address        oldDua;
     const Ip6::Address *oldDuaPtr = nullptr;
     bool                hasDua    = false;
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     Ip6::Address oldMlrRegisteredAddresses[OPENTHREAD_CONFIG_MLE_IP_ADDRS_PER_CHILD - 1];
     uint16_t     oldMlrRegisteredAddressNum = 0;
 #endif
@@ -1986,14 +1986,14 @@ otError MleRouter::UpdateChildAddresses(const Message &aMessage, uint16_t aOffse
     offset = aOffset + sizeof(tlv);
     end    = offset + tlv.GetLength();
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     if ((oldDuaPtr = aChild.GetDomainUnicastAddress()) != nullptr)
     {
         oldDua = *oldDuaPtr;
     }
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     // Retrieve registered multicast addresses of the Child
     if (aChild.HasAnyMlrRegisteredAddress())
     {
@@ -2039,7 +2039,7 @@ otError MleRouter::UpdateChildAddresses(const Message &aMessage, uint16_t aOffse
             address.SetPrefix(context.mPrefix);
             address.SetIid(entry.GetIid());
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
             if (Get<BackboneRouter::Leader>().IsDomainUnicast(address))
             {
                 hasDua = true;
@@ -2118,7 +2118,7 @@ otError MleRouter::UpdateChildAddresses(const Message &aMessage, uint16_t aOffse
         // Clear EID-to-RLOC cache for the unicast address registered by the child.
         Get<AddressResolver>().Remove(address);
     }
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     // Dua is removed
     if (oldDuaPtr != nullptr && !hasDua)
     {
@@ -2126,7 +2126,7 @@ otError MleRouter::UpdateChildAddresses(const Message &aMessage, uint16_t aOffse
     }
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     Get<MlrManager>().UpdateProxiedSubscriptions(aChild, oldMlrRegisteredAddresses, oldMlrRegisteredAddressNum);
 #endif
 
@@ -2436,7 +2436,7 @@ void MleRouter::HandleChildUpdateRequest(const Message &         aMessage,
         ExitNow(error = OT_ERROR_PARSE);
     }
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     if (child->IsCslSynchronized())
     {
         CslChannelTlv cslChannel;
@@ -2457,7 +2457,7 @@ void MleRouter::HandleChildUpdateRequest(const Message &         aMessage,
             child->SetCslChannel(0);
         }
     }
-#endif // OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
 
     child->SetLastHeard(TimerMilli::GetNow());
 
@@ -2468,7 +2468,7 @@ void MleRouter::HandleChildUpdateRequest(const Message &         aMessage,
 
         childDidChange = true;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
         if (child->IsRxOnWhenIdle())
         {
             // Clear CSL synchronization state
@@ -4243,7 +4243,7 @@ void MleRouter::SetChildStateToValid(Child &aChild)
     aChild.SetState(Neighbor::kStateValid);
     IgnoreError(mChildTable.StoreChild(aChild));
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     Get<MlrManager>().UpdateProxiedSubscriptions(aChild, nullptr, 0);
 #endif
 
diff --git a/src/core/thread/mle_tlvs.hpp b/src/core/thread/mle_tlvs.hpp
index 91fa012cc..a70c3a12f 100644
--- a/src/core/thread/mle_tlvs.hpp
+++ b/src/core/thread/mle_tlvs.hpp
@@ -1265,7 +1265,7 @@ public:
     bool IsValid(void) const { return GetLength() >= sizeof(*this) - sizeof(Tlv); }
 } OT_TOOL_PACKED_END;
 
-#if OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE || OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE || (!OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE)
 /**
  * This class implements CSL Channel TLV generation and parsing.
  *
@@ -1330,7 +1330,7 @@ private:
     uint16_t mChannel;
 } OT_TOOL_PACKED_END;
 
-#endif // OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE || OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#endif // OPENTHREAD_CONFIG_MAC_CSL_RECEIVER_ENABLE || (!OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE)
 
 /**
  * @}
diff --git a/src/core/thread/mlr_manager.cpp b/src/core/thread/mlr_manager.cpp
index 3231a9943..287ec602b 100644
--- a/src/core/thread/mlr_manager.cpp
+++ b/src/core/thread/mlr_manager.cpp
@@ -33,7 +33,7 @@
 
 #include "mlr_manager.hpp"
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 
 #include "common/code_utils.hpp"
 #include "common/instance.hpp"
@@ -48,14 +48,14 @@ namespace ot {
 
 MlrManager::MlrManager(Instance &aInstance)
     : InstanceLocator(aInstance)
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     , mRegisterMulticastListenersCallback(nullptr)
     , mRegisterMulticastListenersContext(nullptr)
 #endif
     , mReregistrationDelay(0)
     , mSendDelay(0)
     , mMlrPending(false)
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     , mRegisterMulticastListenersPending(false)
 #endif
 {
@@ -91,7 +91,7 @@ void MlrManager::HandleBackboneRouterPrimaryUpdate(BackboneRouter::Leader::State
 #if OPENTHREAD_CONFIG_MLR_ENABLE
 void MlrManager::UpdateLocalSubscriptions(void)
 {
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     // Check multicast addresses are newly listened against Children
     for (Ip6::ExternalNetifMulticastAddress &addr :
          Get<ThreadNetif>().IterateExternalMulticastAddresses(Ip6::Address::kTypeMulticastLargerThanRealmLocal))
@@ -127,7 +127,7 @@ exit:
 
 #endif // OPENTHREAD_CONFIG_MLR_ENABLE
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 
 bool MlrManager::IsAddressMlrRegisteredByAnyChildExcept(const Ip6::Address &aAddress, const Child *aExceptChild) const
 {
@@ -188,7 +188,7 @@ exit:
     }
 }
 
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 
 void MlrManager::ScheduleSend(uint16_t aDelay)
 {
@@ -253,7 +253,7 @@ void MlrManager::SendMulticastListenerRegistration(void)
     }
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     // Append Child multicast addresses
     for (Child &child : Get<ChildTable>().Iterate(Child::kInStateValid))
     {
@@ -311,7 +311,7 @@ exit:
     CheckInvariants();
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
 otError MlrManager::RegisterMulticastListeners(const otIp6Address *                    aAddresses,
                                                uint8_t                                 aAddressNum,
                                                const uint32_t *                        aTimeout,
@@ -374,7 +374,7 @@ void MlrManager::HandleRegisterMulticastListenersResponse(otMessage *          a
     }
 }
 
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#endif // (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
 
 otError MlrManager::SendMulticastListenerRegistrationMessage(const otIp6Address *  aAddresses,
                                                              uint8_t               aAddressNum,
@@ -404,7 +404,7 @@ otError MlrManager::SendMulticastListenerRegistrationMessage(const otIp6Address
     SuccessOrExit(error = message->Append(addressesTlv));
     SuccessOrExit(error = message->AppendBytes(aAddresses, sizeof(Ip6::Address) * aAddressNum));
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     if (Get<MeshCoP::Commissioner>().IsActive())
     {
         SuccessOrExit(
@@ -539,7 +539,7 @@ void MlrManager::SetMulticastAddressMlrState(MlrState aFromState, MlrState aToSt
         }
     }
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     for (Child &child : Get<ChildTable>().Iterate(Child::kInStateValid))
     {
         for (const Ip6::Address &address : child.IterateIp6Addresses(Ip6::Address::kTypeMulticastLargerThanRealmLocal))
@@ -573,7 +573,7 @@ void MlrManager::FinishMulticastListenerRegistration(bool                aSucces
         }
     }
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     for (Child &child : Get<ChildTable>().Iterate(Child::kInStateValid))
     {
         for (const Ip6::Address &address : child.IterateIp6Addresses(Ip6::Address::kTypeMulticastLargerThanRealmLocal))
@@ -678,7 +678,7 @@ void MlrManager::LogMulticastAddresses(void)
     }
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     for (Child &child : Get<ChildTable>().Iterate(Child::kInStateValid))
     {
         for (const Ip6::Address &address : child.IterateIp6Addresses(Ip6::Address::kTypeMulticastLargerThanRealmLocal))
@@ -696,7 +696,7 @@ void MlrManager::AppendToUniqueAddressList(Ip6::Address (&aAddresses)[kIPv6Addre
                                            uint8_t &           aAddressNum,
                                            const Ip6::Address &aAddress)
 {
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     for (uint8_t i = 0; i < aAddressNum; i++)
     {
         if (aAddresses[i] == aAddress)
@@ -708,7 +708,7 @@ void MlrManager::AppendToUniqueAddressList(Ip6::Address (&aAddresses)[kIPv6Addre
 
     aAddresses[aAddressNum++] = aAddress;
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 exit:
 #endif
     return;
@@ -779,7 +779,7 @@ void MlrManager::CheckInvariants(void) const
         registeringNum += (addr.GetMlrState() == kMlrStateRegistering);
     }
 #endif
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     for (Child &child : Get<ChildTable>().Iterate(Child::kInStateValid))
     {
         for (const Ip6::Address &address : child.IterateIp6Addresses(Ip6::Address::kTypeMulticastLargerThanRealmLocal))
diff --git a/src/core/thread/mlr_manager.hpp b/src/core/thread/mlr_manager.hpp
index d8f6f5ff7..fa2a9f1a3 100644
--- a/src/core/thread/mlr_manager.hpp
+++ b/src/core/thread/mlr_manager.hpp
@@ -36,7 +36,7 @@
 
 #include "openthread-core-config.h"
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 
 #include "backbone_router/bbr_leader.hpp"
 #include "coap/coap_message.hpp"
@@ -93,7 +93,7 @@ public:
     void HandleBackboneRouterPrimaryUpdate(BackboneRouter::Leader::State               aState,
                                            const BackboneRouter::BackboneRouterConfig &aConfig);
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     /**
      * This method updates the Multicast Subscription Table according to the Child information.
      *
@@ -108,11 +108,11 @@ public:
                                     uint16_t            aOldMlrRegisteredAddressNum);
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     /**
      * This method registers Multicast Listeners to Primary Backbone Router.
      *
-     * Note: only available when both `OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE` and
+     * Note: only available when both `(OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)` and
      * `OPENTHREAD_CONFIG_COMMISSIONER_ENABLE` are enabled)
      *
      * @param aAddresses   A pointer to Ip6 multicast addresses to register.
@@ -176,7 +176,7 @@ private:
     bool IsAddressMlrRegisteredByNetif(const Ip6::Address &aAddress) const;
 #endif
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     bool IsAddressMlrRegisteredByAnyChild(const Ip6::Address &aAddress) const
     {
         return IsAddressMlrRegisteredByAnyChildExcept(aAddress, nullptr);
@@ -210,7 +210,7 @@ private:
                                const Ip6::Address *aFailedAddresses,
                                uint8_t             aFailedAddressNum);
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     otIp6RegisterMulticastListenersCallback mRegisterMulticastListenersCallback;
     void *                                  mRegisterMulticastListenersContext;
 #endif
@@ -219,12 +219,12 @@ private:
     uint16_t mSendDelay;
 
     bool mMlrPending : 1;
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
+#if (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE) && OPENTHREAD_CONFIG_COMMISSIONER_ENABLE
     bool mRegisterMulticastListenersPending : 1;
 #endif
 };
 
 } // namespace ot
 
-#endif // OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#endif // OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 #endif // MLR_MANAGER_HPP_
diff --git a/src/core/thread/mlr_types.hpp b/src/core/thread/mlr_types.hpp
index 366a34ea2..c9d642f75 100644
--- a/src/core/thread/mlr_types.hpp
+++ b/src/core/thread/mlr_types.hpp
@@ -36,7 +36,7 @@
 
 #include "openthread-core-config.h"
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 
 namespace ot {
 
@@ -60,5 +60,5 @@ enum MlrState
 
 } // namespace ot
 
-#endif // OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#endif // OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 #endif // MLR_TYPES_HPP_
diff --git a/src/core/thread/neighbor_table.cpp b/src/core/thread/neighbor_table.cpp
index eec83564d..1a25a01e2 100644
--- a/src/core/thread/neighbor_table.cpp
+++ b/src/core/thread/neighbor_table.cpp
@@ -291,7 +291,7 @@ void NeighborTable::Signal(Event aEvent, const Neighbor &aNeighbor)
 
     case OT_NEIGHBOR_TABLE_EVENT_CHILD_REMOVED:
         Get<Notifier>().Signal(kEventThreadChildRemoved);
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
         Get<DuaManager>().UpdateChildDomainUnicastAddress(static_cast<const Child &>(aNeighbor),
                                                           Mle::ChildDuaState::kRemoved);
 #endif
diff --git a/src/core/thread/thread_netif.cpp b/src/core/thread/thread_netif.cpp
index a7a2955dd..f8348bfdd 100644
--- a/src/core/thread/thread_netif.cpp
+++ b/src/core/thread/thread_netif.cpp
@@ -111,11 +111,11 @@ ThreadNetif::ThreadNetif(Instance &aInstance)
     , mBackboneRouterLocal(aInstance)
     , mBackboneRouterManager(aInstance)
 #endif
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
     , mMlrManager(aInstance)
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     , mDuaManager(aInstance)
 #endif
     , mChildSupervisor(aInstance)
diff --git a/src/core/thread/thread_netif.hpp b/src/core/thread/thread_netif.hpp
index 40f8cd0fa..3fee6650c 100644
--- a/src/core/thread/thread_netif.hpp
+++ b/src/core/thread/thread_netif.hpp
@@ -56,11 +56,11 @@
 #include "backbone_router/bbr_manager.hpp"
 #endif
 
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
 #include "thread/mlr_manager.hpp"
 #endif
 
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
 #include "thread/dua_manager.hpp"
 #endif
 
@@ -252,10 +252,10 @@ private:
     BackboneRouter::Local   mBackboneRouterLocal;
     BackboneRouter::Manager mBackboneRouterManager;
 #endif
-#if OPENTHREAD_CONFIG_MLR_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_CONFIG_MLR_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE)
     MlrManager mMlrManager;
 #endif
-#if OPENTHREAD_CONFIG_DUA_ENABLE || OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_CONFIG_DUA_ENABLE || (OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE)
     DuaManager mDuaManager;
 #endif
     Utils::ChildSupervisor     mChildSupervisor;
diff --git a/src/core/thread/topology.cpp b/src/core/thread/topology.cpp
index cd6995369..60b54653b 100644
--- a/src/core/thread/topology.cpp
+++ b/src/core/thread/topology.cpp
@@ -217,7 +217,7 @@ void Child::Info::SetFrom(const Child &aChild)
     mFullThreadDevice   = aChild.IsFullThreadDevice();
     mFullNetworkData    = aChild.IsFullNetworkData();
     mIsStateRestoring   = aChild.IsStateRestoring();
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     mIsCslSynced = aChild.IsCslSynchronized();
 #else
     mIsCslSynced = false;
@@ -269,7 +269,7 @@ void Child::ClearIp6Addresses(void)
 {
     mMeshLocalIid.Clear();
     memset(mIp6Address, 0, sizeof(mIp6Address));
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     mMlrToRegisterMask.Clear();
     mMlrRegisteredMask.Clear();
 #endif
@@ -386,7 +386,7 @@ exit:
     return retval;
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
 const Ip6::Address *Child::GetDomainUnicastAddress(void) const
 {
     const Ip6::Address *addr = nullptr;
@@ -411,7 +411,7 @@ void Child::GenerateChallenge(void)
     IgnoreError(Random::Crypto::FillBuffer(mAttachChallenge, sizeof(mAttachChallenge)));
 }
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 bool Child::HasMlrRegisteredAddress(const Ip6::Address &aAddress) const
 {
     bool has = false;
@@ -454,7 +454,7 @@ void Child::SetAddressMlrState(const Ip6::Address &aAddress, MlrState aState)
     mMlrToRegisterMask.Set(addressIndex, aState == kMlrStateToRegister);
     mMlrRegisteredMask.Set(addressIndex, aState == kMlrStateRegistered);
 }
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 
 void Router::Info::SetFrom(const Router &aRouter)
 {
diff --git a/src/core/thread/topology.hpp b/src/core/thread/topology.hpp
index 49728ade0..bf7f28724 100644
--- a/src/core/thread/topology.hpp
+++ b/src/core/thread/topology.hpp
@@ -698,7 +698,7 @@ private:
 class Child : public Neighbor,
               public IndirectSender::ChildInfo,
               public DataPollHandler::ChildInfo
-#if OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
+#if !OPENTHREAD_MTD && OPENTHREAD_CONFIG_MAC_CSL_TRANSMITTER_ENABLE
     ,
               public CslTxScheduler::ChildInfo
 #endif
@@ -981,7 +981,7 @@ public:
      */
     bool HasIp6Address(const Ip6::Address &aAddress) const;
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_DUA_ENABLE
     /**
      * This method retrieves the Domain Unicast Address registered by the child.
      *
@@ -1094,7 +1094,7 @@ public:
 
 #endif // #if OPENTHREAD_CONFIG_CHILD_SUPERVISION_ENABLE
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     /**
      * This method returns MLR state of an Ip6 multicast address.
      *
@@ -1146,7 +1146,7 @@ public:
      *
      */
     bool HasAnyMlrToRegisterAddress(void) const { return mMlrToRegisterMask.HasAny(); }
-#endif // OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#endif // OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
 
 private:
 #if OPENTHREAD_CONFIG_MLE_IP_ADDRS_PER_CHILD < 2
@@ -1181,7 +1181,7 @@ private:
     Ip6::Address             mIp6Address[kNumIp6Addresses]; ///< Registered IPv6 addresses
     uint32_t                 mTimeout;                      ///< Child timeout
 
-#if OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
+#if OPENTHREAD_FTD && OPENTHREAD_CONFIG_TMF_PROXY_MLR_ENABLE
     ChildIp6AddressMask mMlrToRegisterMask;
     ChildIp6AddressMask mMlrRegisteredMask;
 #endif