diff --git a/src/posix/platform/openthread-posix-config.h b/src/posix/platform/openthread-posix-config.h
index 6d8ab5820..73feb166b 100644
--- a/src/posix/platform/openthread-posix-config.h
+++ b/src/posix/platform/openthread-posix-config.h
@@ -67,4 +67,24 @@
 #define OPENTHREAD_POSIX_VIRTUAL_TIME 0
 #endif
 
+/**
+ * @def OPENTHREAD_POSIX_RCP_UART_ENABLE
+ *
+ * Define as 1 to enable UART interface to RCP.
+ *
+ */
+#ifndef OPENTHREAD_POSIX_RCP_UART_ENABLE
+#define OPENTHREAD_POSIX_RCP_UART_ENABLE 0
+#endif
+
+/**
+ * @def OPENTHREAD_POSIX_RCP_SPI_ENABLE
+ *
+ * Define as 1 to enable SPI interface to RCP.
+ *
+ */
+#ifndef OPENTHREAD_POSIX_RCP_SPI_ENABLE
+#define OPENTHREAD_POSIX_RCP_SPI_ENABLE 0
+#endif
+
 #endif // OPENTHREAD_PLATFORM_CONFIG_H_